MSRB3 and LNX2

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		MSRB3	LNX2
Description		methionine sulfoxide reductase B3	ligand of numb-protein X 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Peptide-methionine (R)-S-oxide Reductase Activity L-methionine-(R)-S-oxide Reductase Activity	Protein Binding PDZ Domain Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Response To Oxidative Stress Protein Repair Oxidation-reduction Process
Pathways		Protein repair
Drugs
Diseases
GWAS		Antisaccade task score ( 31596458) Birth weight ( 31043758) Dentate gyrus granule cell layer volume ( 30279459) Dentate gyrus molecular layer volume ( 30279459) Differentiated thyroid cancer ( 28703219) FEV1 ( 30804560) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549) Height ( 31562340) Hippocampal fissure volume ( 30279459) Hippocampal subfield CA1 volume ( 30279459) Hippocampal subfield CA1 volume (corrected for total hippocampal volume) ( 30279459) Hippocampal subfield CA3 volume ( 30279459) Hippocampal subfield CA4 volume ( 30279459) Hippocampal volume ( 28098162 22504421) Lung function (FEV1) ( 28166213) Lung function (FVC) ( 30804560) Papillary thyroid cancer ( 28703219) Peak expiratory flow ( 30804560) Post bronchodilator FEV1/FVC ratio ( 26634245) Primary tooth development (number of teeth) ( 23704328 20195514) Primary tooth development (time to first tooth eruption) ( 23704328 20195514) Subcortical brain region volumes ( 25607358) Subiculum volume ( 30279459) Temperament ( 22832960) Temporal lobe volume ( 31396565) Total hippocampal volume ( 30279459) Type 2 diabetes nephropathy ( 21150874)	Body mass index ( 26426971 28892062) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 27863252) Night sleep phenotypes ( 27126917) Platelet distribution width ( 27863252) Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Interacting Genes		6 interacting genes: GOLGA2 LNX2 MAPK8IP2 PRDM4 TCF4 TRIP6	89 interacting genes: ATP5F1B C10orf88 CABP4 CBX4 CCT3 CDK2 CDK4 CDKN2C CRK CXADR DDA1 DRAP1 EAF2 FANCG FHL3 GADD45A GJD2 GLRX3 GRAP2 GRB2 IGSF5 IL16 INMT IP6K2 L3MBTL2 LGALS14 LNX1 LRRC8E MAP2K5 MAPK9 MCM7 MDGA1 MLX MRFAP1L1 MSRB3 MYLIP NAGK NMD3 NOTCH1 NTAQ1 NUDT14 NUMB OPTN PARVG PDZRN3 PDZRN4 PEG10 PHYKPL PIK3R1 PIK3R3 PKDREJ POLR1C PPIH PPIL1 PSMD5 PSMF1 PTCD3 RAB6B RBM17 RLIM RNF138 ROPN1 RPA2 SCLY SCNM1 SFN SH3GLB2 SHISA2 SHTN1 SMARCB1 SRSF11 TAB1 TBC1D7 TCL1A TIFA TRAF1 TRAF2 TUBB UBE2D2 UBE2H UBE2I UBE2T UBE2Z USP2 VTN YJU2 ZNF148 ZNF410 ZNF581
Entrez ID		253827	222484
HPRD ID		14785	10042
Ensembl ID		ENSG00000174099	ENSG00000139517
Uniprot IDs		Q8IXL7	Q8N448
PDB IDs			2VWR 5DIN 5E11 5E1Y 5E21 5E22
Enriched GO Terms of Interacting Partners?
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