WDR27 and ASNS

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		WDR27	ASNS
Description		WD repeat domain 27	asparagine synthetase (glutamine-hydrolyzing)
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Cytosol
	Molecular Function	Protein Binding	Asparagine Synthase (glutamine-hydrolyzing) Activity Protein Binding ATP Binding Identical Protein Binding Cofactor Binding
	Biological Process		Liver Development Asparagine Biosynthetic Process Glutamine Metabolic Process Cellular Amino Acid Biosynthetic Process Response To Light Stimulus Response To Mechanical Stimulus Response To Toxic Substance Response To Methotrexate Response To Follicle-stimulating Hormone Cellular Response To Hormone Stimulus PERK-mediated Unfolded Protein Response Cellular Response To Glucose Starvation Negative Regulation Of Apoptotic Process Response To Amino Acid Positive Regulation Of Mitotic Cell Cycle L-asparagine Biosynthetic Process
Pathways			ATF4 activates genes in response to endoplasmic reticulum stress Aspartate and asparagine metabolism Response of EIF2AK4 (GCN2) to amino acid deficiency Response of EIF2AK1 (HRI) to heme deficiency
Drugs			L-Aspartic Acid Glutamic Acid ATP L-Asparagine
Diseases
GWAS		Eye morphology ( 29921221) Insomnia ( 27992416) Insomnia complaints ( 28604731) Response to anti-TNF therapy in rheumatoid arthritis ( 26776603) Type 1 diabetes ( 21980299)	Regular attendance at a religious group ( 29970889) Tuberculosis ( 30713548)
Interacting Genes		1 interacting genes: ASNS	5 interacting genes: ATXN1 RAB8A STRN4 TRIM69 WDR27
Entrez ID		253769	440
HPRD ID		11352	00153
Ensembl ID		ENSG00000184465	ENSG00000070669
Uniprot IDs		A2RRH5	P08243
PDB IDs			6GQ3
Enriched GO Terms of Interacting Partners?
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