ALPP and GPLD1

Number of citations of the paper that reports this interaction (PubMedID 11938765)
0

Data Source:
HPRD (in vitro)

		ALPP	GPLD1
Description		alkaline phosphatase, placental	glycosylphosphatidylinositol specific phospholipase D1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane Anchored Component Of Membrane	Extracellular Region Extracellular Space Cytoplasm Lysosomal Membrane Extracellular Matrix Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Magnesium Ion Binding Alkaline Phosphatase Activity Protein Binding Zinc Ion Binding	Glycosylphosphatidylinositol Phospholipase D Activity Phospholipase D Activity Sodium Channel Regulator Activity
	Biological Process	Dephosphorylation	Ossification Cell Migration Involved In Sprouting Angiogenesis Chondrocyte Differentiation Complement Receptor Mediated Signaling Pathway C-terminal Protein Lipidation GPI Anchor Release Negative Regulation Of Cell Proliferation Insulin Receptor Signaling Pathway Response To Glucose Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Alkaline Phosphatase Activity Positive Regulation Of Triglyceride Biosynthetic Process Negative Regulation Of Triglyceride Catabolic Process Positive Regulation Of Glucose Metabolic Process Positive Regulation Of High-density Lipoprotein Particle Clearance Cellular Response To Insulin Stimulus Cellular Response To Drug Hematopoietic Stem Cell Migration Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Apoptotic Process Phosphatidylcholine Metabolic Process Positive Regulation Of Membrane Protein Ectodomain Proteolysis Positive Regulation Of Secretion Transepithelial Transport Cellular Response To Calcium Ion Cellular Response To Cholesterol Cellular Response To Triglyceride Cellular Response To PH Hematopoietic Stem Cell Migration To Bone Marrow Regulation Of Cellular Response To Insulin Stimulus
Pathways		Intra-Golgi traffic	Post-translational modification: synthesis of GPI-anchored proteins
Drugs		Calcium METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER
Diseases
GWAS		Blood protein levels ( 30072576) Height ( 19570815)	Hematological and biochemical traits ( 20139978) Liver enzyme levels ( 18940312) Liver enzyme levels (alkaline phosphatase) ( 22001757) Serum alkaline phosphatase levels ( 31666285 29403010)
Interacting Genes		8 interacting genes: ALPG GPLD1 KRTAP10-3 KRTAP4-12 KRTAP5-9 LATS1 NLGN3 PIGK	5 interacting genes: ALPP APOA1 APOA4 CD55 GM2A
Entrez ID		250	2822
HPRD ID		01379	03946
Ensembl ID		ENSG00000163283	ENSG00000112293
Uniprot IDs		B2R7C7 P05187	P80108
PDB IDs		1EW2 1ZEB 1ZED 1ZEF 2GLQ 3MK0 3MK1 3MK2
Enriched GO Terms of Interacting Partners?
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