FRZB and ELF5

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		FRZB	ELF5
Description		frizzled related protein	E74 like ETS transcription factor 5
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Membrane	Nuclear Chromatin Nucleus Cytoplasm
	Molecular Function	Wnt-protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
	Biological Process	Skeletal System Development Negative Regulation Of Cell Proliferation Negative Regulation Of Cell Development Neural Crest Cell Differentiation Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Cell Growth Non-canonical Wnt Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Fat Cell Differentiation Convergent Extension Involved In Organogenesis Canonical Wnt Signaling Pathway Negative Regulation Of Cartilage Development Somite Development Negative Regulation Of Hepatocyte Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Cochlea Morphogenesis	Ectodermal Cell Fate Commitment Regulation Of Transcription By RNA Polymerase II Cell Differentiation Somatic Stem Cell Population Maintenance Negative Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Mammary Gland Epithelial Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Heel bone mineral density ( 30598549 28869591) Neurological blood protein biomarker levels ( 31320639) Night sleep phenotypes ( 27126917) Waist-to-hip circumference ratio (dietary energy interaction) ( 23192594) Working memory ( 31598132)	β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374) Blood protein levels ( 28240269) Metabolite levels ( 23823483)
Interacting Genes		7 interacting genes: BBS10 EHF ELF5 PNO1 POLA2 RBX1 SMAD1	8 interacting genes: ACTR2 FRZB NFE2 NRIP2 RPS15A SIRT6 SS18L1 UBQLN4
Entrez ID		2487	2001
HPRD ID		07282	05525
Ensembl ID		ENSG00000162998	ENSG00000135374
Uniprot IDs		D9ZGF6 Q92765	A0A087X1W9 A8K443 Q9UKW6
PDB IDs			1WWX
Enriched GO Terms of Interacting Partners?
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