HSPBP1 and HSPA9

Number of citations of the paper that reports this interaction (PubMedID 19659607)
15

Data Source:
HPRD (in vitro)

		HSPBP1	HSPA9
Description		HSPA (Hsp70) binding protein 1	heat shock protein family A (Hsp70) member 9
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum	Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix Focal Adhesion Mitochondrial Nucleoid Extracellular Exosome
	Molecular Function	Adenyl-nucleotide Exchange Factor Activity Enzyme Inhibitor Activity Protein Binding Ubiquitin Protein Ligase Binding	RNA Binding Protein Binding ATP Binding ATPase Activity Heat Shock Protein Binding Ubiquitin Protein Ligase Binding ATPase Activity, Coupled Protein Binding Involved In Protein Folding Unfolded Protein Binding Misfolded Protein Binding
	Biological Process	Protein Folding Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Catalytic Activity	Protein Export From Nucleus Response To Unfolded Protein Iron-sulfur Cluster Assembly Erythrocyte Differentiation Cellular Response To Unfolded Protein Interleukin-12-mediated Signaling Pathway Protein Refolding Negative Regulation Of Apoptotic Process Regulation Of Erythrocyte Differentiation Negative Regulation Of Erythrocyte Differentiation Chaperone Cofactor-dependent Protein Refolding Negative Regulation Of Hematopoietic Stem Cell Differentiation
Pathways			Mitochondrial protein import Regulation of HSF1-mediated heat shock response Cristae formation Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) Schizophrenia ( 25056061 29483656)
Interacting Genes		11 interacting genes: APP CLK1 HSPA1A HSPA1B HSPA2 HSPA4 HSPA5 HSPA8 HSPA9 LRIF1 NOTCH2NLA	22 interacting genes: APP DNAJC19 DNLZ FGF1 HSP90B1 HSPBP1 LSM8 MATK MVD NELFB PTPN11 PTPRF SIRPA STUB1 SUMO2 SUMO4 SUPT6H TIMM44 TP53 XPO1 YKT6 YWHAG
Entrez ID		23640	3313
HPRD ID		09991	02770
Ensembl ID		ENSG00000133265	ENSG00000113013
Uniprot IDs		Q9NZL4	A0A384P5G6 P38646
PDB IDs		1XQR 1XQS	3N8E 4KBO 6NHK 6P2U
Enriched GO Terms of Interacting Partners?
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