WBP2 and EPN2

Number of citations of the paper that reports this interaction (PubMedID 27578003)
17

Data Source:
BioGRID (two hybrid)

		WBP2	EPN2
Description		WW domain binding protein 2	epsin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytoplasm	Cytosol Clathrin Coat Of Endocytic Vesicle Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Estrogen Receptor Binding Chromatin DNA Binding	Protein Binding Lipid Binding Cadherin Binding
	Biological Process	Response To Progesterone Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Estrogen Establishment Of Protein Localization Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Progesterone Receptor Signaling Pathway Cellular Response To Estrogen Stimulus Positive Regulation Of Histone H3-K14 Acetylation	Endocytosis Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Notch Signaling Pathway Membrane Organization Negative Regulation Of Sprouting Angiogenesis
Pathways			Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS			Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diastolic blood pressure ( 30224653)
Interacting Genes		47 interacting genes: ANAPC1 ANKRD13A ANKRD13D ARCN1 CLEC4G COPA COPB1 COPB2 COPE COPG1 CUEDC1 DDX17 EEF1B2 EPN2 ESR1 GRPEL1 H4C1 HUWE1 ITCH KRT18 KRT8 KRT9 MAGEA4 MAGI1 MYO6 NEDD4 NEDD4L PAX8 POLH RHBDD3 RNF168 RPS27A RPS3 SDHA SEPTIN3 TDP2 TOLLIP TOM1L2 UBA52 UBC UBE3A UBQLN1 UIMC1 WWP1 WWP2 WWTR1 YAP1	11 interacting genes: APOE CLTC EPS15 ITSN1 LAPTM5 RNF11 TFAP2A TUBA1B UBC WBP2 YWHAG
Entrez ID		23558	22905
HPRD ID		06097	06271
Ensembl ID		ENSG00000132471	ENSG00000072134
Uniprot IDs		A0A024R8L1 Q969T9	O95208
PDB IDs
Enriched GO Terms of Interacting Partners?
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