TSPAN15 and SYNE4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TSPAN15	SYNE4
Description		tetraspanin 15	spectrin repeat containing nuclear envelope family member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Late Endosome Membrane Tetraspanin-enriched Microdomain	Integral Component Of Nuclear Outer Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	Protein Binding Enzyme Binding	Protein Binding
	Biological Process	Regulation Of Notch Signaling Pathway Cellular Protein Metabolic Process Negative Regulation Of Notch Signaling Pathway Protein Maturation Protein Localization To Plasma Membrane	Establishment Of Epithelial Cell Apical/basal Polarity
Pathways		Amyloid fiber formation
Drugs
Diseases
GWAS		Height ( 31562340) Response to taxane treatment (placlitaxel) ( 23006423) Thrombosis ( 26908601) Venous thromboembolism ( 25772935 28373160 31420334 31676865)
Interacting Genes		3 interacting genes: BTRC RGS2 SYNE4	51 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B ZNF250
Entrez ID		23555	163183
HPRD ID		15511	08776
Ensembl ID		ENSG00000099282	ENSG00000181392
Uniprot IDs		O95858	Q8N205
PDB IDs
Enriched GO Terms of Interacting Partners?
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