SF3B1 and SF3B6

Number of citations of the paper that reports this interaction (PubMedID 11500380)
69

Data Source:
HPRD (in vitro)

		SF3B1	SF3B6
Description		splicing factor 3b subunit 1	splicing factor 3b subunit 6
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2 SnRNP U12-type Spliceosomal Complex Nuclear Speck U11/U12 SnRNP U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm U12-type Spliceosomal Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding Splicing Factor Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing Positive Regulation Of Gene Expression, Epigenetic	MRNA Splicing, Via Spliceosome Blastocyst Formation
Pathways		B-WICH complex positively regulates rRNA expression mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Major depressive disorder ( 27479909) Morning person ( 30696823) Schizophrenia ( 25056061 29483656 30285260)
Interacting Genes		24 interacting genes: APBB1 C11orf58 CALM1 CLK1 CSNK2A1 DYRK1A ERG IL7R MELK MYC NUDT21 PLRG1 PPP1R8 PRPF40A SF1 SF3B3 SF3B6 SMAD1 SMAD5 SMAD9 SNIP1 TCERG1 TOP1 WBP4	2 interacting genes: APP SF3B1
Entrez ID		23451	51639
HPRD ID		09281	09702
Ensembl ID		ENSG00000115524	ENSG00000115128
Uniprot IDs		B4DGZ4 O75533	Q9Y3B4
PDB IDs		2F9D 2F9J 2FHO 2PEH 3LQV 4OZ1 5IFE 5O9Z 5Z56 5Z57 5Z58 5ZYA 6AH0 6EN4 6FF4 6FF7 6N3E 6QX9	2F9D 2F9J 2FHO 3LQV 5Z56 5Z57 5Z58 6AH0 6FF4 6FF7
Enriched GO Terms of Interacting Partners?
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