ZDHHC17 and GRB10

Number of citations of the paper that reports this interaction (PubMedID 24705354)
18

Data Source:
BioGRID (two hybrid)

		ZDHHC17	GRB10
Description		zinc finger DHHC-type palmitoyltransferase 17	growth factor receptor bound protein 10
Image
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane Aggresome Cell Junction Cytoplasmic Vesicle Membrane Golgi-associated Vesicle Membrane Presynaptic Membrane Cell Projection Intracellular Membrane-bounded Organelle	Cytoplasm Cytosol Plasma Membrane Protein-containing Complex
	Molecular Function	Protein Binding Magnesium Ion Transmembrane Transporter Activity Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity Identical Protein Binding	SH3/SH2 Adaptor Activity Insulin Receptor Binding Protein Binding
	Biological Process	Protein Palmitoylation Lipoprotein Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Magnesium Ion Transmembrane Transport	Axon Guidance Insulin Receptor Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Glucose Import Negative Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis
Pathways			Signaling by SCF-KIT IRS activation Signal attenuation Insulin receptor signalling cascade RET signaling Response of EIF2AK1 (HRI) to heme deficiency
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Visceral fat ( 30942860)	Acute lymphoblastic leukemia (childhood) ( 23512250) Area under the curve of insulin levels ( 24699409) Birth weight ( 31043758) Blood pressure (smoking interaction) ( 25189868) Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Chronotype ( 30696823) Corpus callosum mid-anterior volume ( 31530798) Corrected insulin response ( 24699409) Corrected insulin response adjusted for insulin sensitivity index ( 24699409) Diastolic blood pressure ( 30224653) Eosinophil counts ( 27863252) Estimated glomerular filtration rate ( 31152163 31015462) Fasting blood glucose ( 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Femoral neck bone mineral density ( 22504420) Fractures ( 30158200) Heel bone mineral density ( 30598549) Incremental insulin ( 24699409) Insulin levels adjusted for BMI ( 24699409) Metabolite levels ( 23823483) Morning person ( 30696823) Ratio of the area under the curve for insulin and the area under the curve for glucose ( 24699409) Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901) Schizophrenia (treatment resistant) ( 25223841) Sum eosinophil basophil counts ( 27863252) Systemic sclerosis ( 21779181) Total body bone mineral density ( 29304378)
Interacting Genes		192 interacting genes: - ABCG4 ACTR1B ADD1 AHDC1 AIDA AK3 ALKBH3 ANKRD50 ANXA11 APBB1IP ARFGAP3 ASF1A ASIC4 BCAS3 BEX2 BTF3 C1orf216 C20orf141 CBS CCDC120 CCDC7 CCNE2 CDSN CENPBD1P1 CHMP1A CIB1 CLRN3 CNDP2 CNKSR1 COG3 CSTA CTCFL CTHRC1 DALRD3 DELE1 DIXDC1 DLG4 DLK1 DR1 DTX3 E2F8 EDRF1 EEF1G ERCC6L EVL EXOSC9 EYA3 FAM122C FAM207A FAM9A FBH1 FOXD4L6 FTL FUT2 FUT9 GABPB1 GABPB2 GATA1 GOLPH3L GPR135 GRB10 GUSBP3 H2AP H2BC9 H3C10 HBG1 HECTD3 HLA-A HLA-DRB1 HMBS HOXA3 HS1BP3 HTT IFT20 IFT57 INPP5D JMJD7-PLA2G4B KHDC4 KIAA0408 KNSTRN KRAS KRT17 KRT8P12 KRTAP11-1 KRTAP9-2 LCA5L LGALS9C LIN28A LMAN2L LNCRI LRRC45 LY6G6C MANF MAP3K19 MIIP MLH3 MRFAP1 MRFAP1L1 MSANTD3 MSRB2 MYBPHL MYOZ2 NCBP1 NEBL NFATC2IP NFYC NIFK NPFF ODF2 OFCC1 OTUD7B OTX2 PBRM1 PDE4DIP PDZK1IP1 PHF5A PLEKHB1 PPP1R21 PPTC7 PRMT5 PTMA QRICH1 RAB39B RAD51 RANGRF RAP1B RBM5 RCAN3 RIC8A RNF20 RNF38 RSBN1L RUBCNL SCNM1 SEMA4G SF3A3 SHOX2 SKA3 SLC1A3 SLC25A31 SLC9A9 SMARCB1 SNAP25 SOX14 SP2 SPRED2 SPRY4 SREBF2 SRSF4 STK25 STN1 SUMF2 SYT1 TEAD1 THAP7 TIGD1 TMC6 TMCC1 TMEM115 TMEM186 TMTC1 TNFAIP1 TNFSF10 TOX TPGS2 TTC23 TTLL7 TUT7 TXNDC12 TXNDC15 UBAC1 UBE2K USP18 USP32 VN1R10P VSX2 WAC WDR20 YIF1A YTHDF3 ZCCHC17 ZFC3H1 ZFP2 ZFP36 ZFYVE19 ZNF333 ZNF341 ZNF597 ZNF624 ZNF667-AS1 ZSCAN9	32 interacting genes: ABL1 AKT1 APP BAIAP2 BCR CHFR CNOT9 DOK1 EGFR ELK1 EPHB1 FYN GHR GIGYF1 GIGYF2 IGF1R INSR IRS1 JAK2 KDR KIT MAP2K1 MAP3K14 MAPK1 MEGF10 NEDD4 NOA1 PDGFRB RAF1 RET SRC ZDHHC17
Entrez ID		23390	2887
HPRD ID		09697	03312
Ensembl ID		ENSG00000186908	ENSG00000106070
Uniprot IDs		Q8IUH5	Q13322
PDB IDs		3EU9 5W7I 5W7J	1NRV 3HK0
Enriched GO Terms of Interacting Partners?
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