JADE2 and PACSIN1

Number of citations of the paper that reports this interaction (PubMedID 20936779)
85

Data Source:
BioGRID (two hybrid)

		JADE2	PACSIN1
Description		jade family PHD finger 2	protein kinase C and casein kinase substrate in neurons 1
Image		No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Extracellular Exosome	Cytoplasm Endosome Cytosol Cytoskeleton Plasma Membrane Cell Junction COPI-coated Vesicle Cytoplasmic Vesicle Membrane Ruffle Membrane Axon Terminus Synapse Perinuclear Region Of Cytoplasm Photoreceptor Ribbon Synapse Presynaptic Endocytic Zone
	Molecular Function	Protein Binding Transferase Activity Metal Ion Binding	Protein Binding Phospholipid Binding Cytoskeletal Protein Binding Identical Protein Binding
	Biological Process	Protein Ubiquitination Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation	Cytoskeleton Organization Actin Filament Organization Regulation Of Endocytosis Negative Regulation Of Endocytosis Synaptic Vesicle Endocytosis Neuron Projection Morphogenesis Protein Localization To Membrane Protein Localization To Plasma Membrane Plasma Membrane Tubulation Positive Regulation Of Dendrite Development
Pathways		HATs acetylate histones	Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Age at first birth ( 27798627) Body mass index ( 28892062) Coffee consumption ( 31046077) Hand grip strength ( 29691431) Household income (MTAG) ( 31844048) Mental health study participation (completed survey) ( 31263887) Multiple sclerosis ( 31604244) Platelet distribution width ( 27863252) Type 2 diabetes ( 28869590)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29273807 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Free thyroxine concentration ( 30367059) High density lipoprotein cholesterol levels ( 30498476) Inflammatory bowel disease ( 27569725) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		9 interacting genes: FBXO7 GORASP2 H3-4 ING5 PACSIN1 SASH1 ZBTB3 ZBTB5 ZNF496	24 interacting genes: ANKRD24 ARHGAP17 DNM1 EHBP1 FTH1 GAS7 HTT ITCH JADE2 KAT7 KHDRBS1 MAPT MT-ATP8 PACSIN2 PACSIN3 POT1 RTKN2 SOS1 SPTBN1 SYNJ1 TPM4 TRPV4 WASF2 WASL
Entrez ID		23338	29993
HPRD ID		15124	05936
Ensembl ID		ENSG00000043143	ENSG00000124507
Uniprot IDs		A0A0C4DFT8 B3KPL2 B4DFY8 G3XAA4 Q9NQC1	Q5TZC3 Q9BY11
PDB IDs			3HAH 3HAI 3Q84 3QNI
Enriched GO Terms of Interacting Partners?
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