DNAJC13 and RPS6KA6

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		DNAJC13	RPS6KA6
Description		DnaJ heat shock protein family (Hsp40) member C13	ribosomal protein S6 kinase A6
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Cytosol Plasma Membrane Endosome Membrane Membrane Secretory Granule Membrane Early Endosome Membrane Azurophil Granule Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome WASH Complex	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Ribosomal Protein S6 Kinase Activity ATP Binding
	Biological Process	Osteoblast Differentiation Receptor-mediated Endocytosis Endosome Organization Protein Transport Neutrophil Degranulation Regulation Of Early Endosome To Recycling Endosome Transport Regulation Of Early Endosome To Late Endosome Transport	Protein Phosphorylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Signal Transduction Central Nervous System Development Intracellular Signal Transduction Negative Regulation Of Embryonic Development Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Mesoderm Development
Pathways		Neutrophil degranulation	Recycling pathway of L1 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling RSK activation RSK activation
Drugs
Diseases
GWAS		Blood protein levels ( 29875488 28240269) Body mass index ( 26426971) Coronary artery disease ( 29212778) Iron status biomarkers (total iron binding capacity) ( 28334935) LDL cholesterol ( 30275531) Red cell distribution width ( 27863252 28957414) Total cholesterol levels ( 30275531) Urate levels ( 31578528)
Interacting Genes		6 interacting genes: CALM1 CLK1 DNAJB11 GADD45A GSK3B RPS6KA6	27 interacting genes: ADIRF APP CEBPZ CENPB CLEC3B DHX34 DNAJC13 DNMT1 ERG28 FBN3 FZD5 LMO4 MASP1 MED24 MICAL1 MPP1 NR4A1 RBPJ RPLP1 RXRA SAP30BP SPTBN4 SYNE4 UBE2I UFM1 ZNF227 ZNF746
Entrez ID		23317	27330
HPRD ID		10915	02250
Ensembl ID		ENSG00000138246	ENSG00000072133
Uniprot IDs		B3KN02 O75165	Q9UK32
PDB IDs			6G76 6G77 6G78
Enriched GO Terms of Interacting Partners?
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