MCF2L and AIMP2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		MCF2L	AIMP2
Description		MCF.2 cell line derived transforming sequence like	aminoacyl tRNA synthetase complex interacting multifunctional protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytosol Plasma Membrane Endomembrane System	Nucleus Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Phosphatidylinositol Binding	Protein Binding Molecular Adaptor Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Regulation Of Small GTPase Mediated Signal Transduction	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation Protein-containing Complex Assembly Positive Regulation Of Neuron Death Positive Regulation Of Aminoacyl-tRNA Ligase Activity
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events	Selenoamino acid metabolism Cytosolic tRNA aminoacylation
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Diastolic blood pressure ( 27841878) Factor VII ( 17903294) Osteoarthritis ( 21871595) Pulse pressure ( 27841878 30578418) Systolic blood pressure ( 28135244 27841878 30578418)	Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		7 interacting genes: AIMP2 CDC42 RABAC1 RAC1 RHOA RHOG YAE1	48 interacting genes: ACTB AIMP1 APP BCAS2 BEX3 BLOC1S4 BYSL C19orf57 CEP126 CHD3 DARS1 DARS2 DEAF1 DSN1 EPRS1 EPS8 FGB FHL3 FUBP1 GYS1 ICE1 KARS1 KDR KLC2 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIS18A NDEL1 NECAB2 PCMT1 PLEKHF2 PPP2R1A PRKAA2 PRKN PSME1 SMURF2 TANK TERF2IP TFIP11 TP53 TRAF2 TRMT2A ZC3H12A ZGPAT
Entrez ID		23263	7965
HPRD ID		14371	02915
Ensembl ID		ENSG00000126217	ENSG00000106305
Uniprot IDs		O15068	A0A024QZY1 A8MU58 Q13155
PDB IDs			4DPG 4YCU 4YCW 5A1N 5A34 5A5H 5Y6L 6ILD 6IY6 6JPV 6K39
Enriched GO Terms of Interacting Partners?
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