PLCL2 and DSCAML1

Number of citations of the paper that reports this interaction (PubMedID 12421765)
39

Data Source:
HPRD (two hybrid)

		PLCL2	DSCAML1
Description		phospholipase C like 2	DS cell adhesion molecule like 1
Image		No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm	Extracellular Space Plasma Membrane Cell Surface Integral Component Of Membrane Cell Junction Axon Synapse
	Molecular Function	Phosphatidylinositol Phospholipase C Activity GABA Receptor Binding Inositol 1,4,5 Trisphosphate Binding	Protein Homodimerization Activity Cell-cell Adhesion Mediator Activity
	Biological Process	B Cell Proliferation Involved In Immune Response B-1a B Cell Differentiation Lipid Metabolic Process Gamma-aminobutyric Acid Signaling Pathway Regulation Of Synaptic Transmission, GABAergic Inositol Trisphosphate Biosynthetic Process Regulation Of Peptidyl-serine Phosphorylation Phosphatidylinositol-mediated Signaling Negative Regulation Of B Cell Receptor Signaling Pathway Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Cold-induced Thermogenesis Positive Regulation Of Receptor Binding	Cell Fate Determination Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axonogenesis Axon Guidance Central Nervous System Development Brain Development Dorsal/ventral Pattern Formation Embryonic Skeletal System Morphogenesis Dendrite Self-avoidance
Pathways			DSCAM interactions
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Cognitive ability (MTAG) ( 29186694) General factor of neuroticism ( 30867560) Intelligence ( 28530673) Lung cancer ( 28604730) Mean corpuscular hemoglobin ( 29403010 27863252 28017375) Mean corpuscular volume ( 29403010 27863252 28017375) Mood instability ( 31168069) Multiple sclerosis ( 21833088) Multiple sclerosis and HDL levels (pleiotropy) ( 26920376) Myocardial infarction ( 24916648) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952) Neurociticism ( 29500382) Primary biliary cholangitis ( 21399635 26394269) Psoriasis ( 25939698) Psoriasis vulgaris ( 26626624) Red blood cell count ( 29403010 27863252) Rheumatoid arthritis ( 30423114 24390342) Sum eosinophil basophil counts ( 27863252)	Hippocampal volume in Alzheimer's disease dementia ( 29274321) Lipoprotein (a) - cholesterol levels ( 25575512) Menarche (age at onset) ( 23599027) Myopia ( 27182965) Putamen volume ( 29147026) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Triglyceride levels ( 28548082) Triglycerides ( 19074352 30275531) Very low density lipoprotein cholesterol levels ( 28548082)
Interacting Genes		2 interacting genes: DSCAML1 PPP1CA	3 interacting genes: MAGI2 MAGI3 PLCL2
Entrez ID		23228	57453
HPRD ID		07147	10921
Ensembl ID		ENSG00000154822	ENSG00000177103
Uniprot IDs		Q9UPR0	A0A384DVL8 Q8TD84
PDB IDs			1VA9
Enriched GO Terms of Interacting Partners?
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