RGL1 and RIT1

Number of citations of the paper that reports this interaction (PubMedID 10545207)
24

Data Source:
HPRD (in vitro)

		RGL1	RIT1
Description		ral guanine nucleotide dissociation stimulator like 1	Ras like without CAAX 1
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol	Plasma Membrane
	Molecular Function	Protein Binding Ral Guanyl-nucleotide Exchange Factor Activity	GTPase Activity Protein Binding Calmodulin Binding GTP Binding GDP Binding
	Biological Process	Small GTPase Mediated Signal Transduction Regulation Of Lipid Metabolic Process	Signal Transduction Ras Protein Signal Transduction
Pathways		PPARA activates gene expression	Signalling to p38 via RIT and RIN
Drugs
Diseases
GWAS		Antipsychotic drug-induced QTc interval change in schizophrenia ( 29064910) Aspartate aminotransferase levels ( 29403010) Attention deficit hyperactivity disorder and conduct disorder ( 18951430) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954) Response to antidepressants ( 20360315) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)	Birth weight ( 31043758) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Conduct disorder (maternal expressed emotions interaction) ( 18846501) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233)
Interacting Genes		4 interacting genes: APP HRAS RIT1 RIT2	15 interacting genes: AFDN AP2A1 CUL3 IFRD1 KLHL12 LRIF1 LRRK2 PTN RALGDS RGL1 RLF SMAD2 SMAD3 SMURF1 SRPK2
Entrez ID		23179	6016
HPRD ID		12032	10195
Ensembl ID		ENSG00000143344	ENSG00000143622
Uniprot IDs		B7Z2W5 B7Z915 B7ZB61 Q9NZL6	Q92963
PDB IDs			4KLZ
Enriched GO Terms of Interacting Partners?
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