GGA2 and TOLLIP

Number of citations of the paper that reports this interaction (PubMedID 15047686)
46

Data Source:
BioGRID (pull down)

		GGA2	TOLLIP
Description		golgi associated, gamma adaptin ear containing, ARF binding protein 2	toll interacting protein
Image
GO Annotations	Cellular Component	Golgi Apparatus Trans-Golgi Network Endosome Membrane Clathrin-coated Vesicle Early Endosome Membrane	Extracellular Region Cytoplasm Cytosol Nuclear Body Azurophil Granule Lumen Specific Granule Lumen Interleukin-18 Receptor Complex Interleukin-1 Receptor Complex Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding ADP-ribosylation Factor Binding	Interleukin-1, Type I Receptor Binding Protein Binding Kinase Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin Protein Ligase Binding SUMO Binding Toll-like Receptor Binding Ubiquitin Binding
	Biological Process	Intracellular Protein Transport Protein Localization To Cell Surface Golgi To Plasma Membrane Protein Transport Cellular Protein Metabolic Process	Ubiquitin-dependent Protein Catabolic Process Autophagy Inflammatory Response Signal Transduction Cell-cell Signaling Phosphorylation Epithelial Cell Differentiation Positive Regulation Of Protein Sumoylation Intracellular Signal Transduction Protein Localization To Endosome Neutrophil Degranulation Innate Immune Response Leukocyte Activation Interleukin-1-mediated Signaling Pathway
Pathways		TBC/RABGAPs Amyloid fiber formation	Neutrophil degranulation Interleukin-1 signaling
Drugs
Diseases
GWAS			Idiopathic pulmonary fibrosis ( 24429156)
Interacting Genes		34 interacting genes: ADRA2B AFTPH APP ARF1 ARF3 ATXN1 BACE1 BACE2 CA8 CCDC91 CLINT1 CLTC FBXO7 GGA1 GGA3 GOLGA2 HGS HTT IGF2R LRP3 M6PR MAP3K1 PIN1 RABEP1 RABGEF1 RNF11 SORL1 SORT1 SPG21 STAB1 SYNRG TOLLIP TRIM23 VPS18	44 interacting genes: ACTN2 ATXN1 BHLHE40 CHD6 CPSF6 CSN1S1 CSN2 CSTF1 DAB1 DAZAP2 DZIP3 EIF2AK2 FTH1 GGA1 GGA2 GGA3 HERPUD1 IL1R1 IL1RAP IRAK1 IRAK2 LDB1 N4BP2 NTAQ1 ODAM PEG10 PRR20A RBFOX2 RBPMS RHOXF2 SEPTIN1 SETDB1 SIAH1 TBX3 TLR2 TLR4 TOM1 TOM1L1 UBC WBP2 WRNIP1 XRN2 ZBTB16 ZHX1
Entrez ID		23062	54472
HPRD ID		09347	05887
Ensembl ID		ENSG00000103365	ENSG00000078902
Uniprot IDs		Q9UJY4	B3KR28 E9PNS3 F2Z2Y8 Q6FIE9 Q8N8J5 Q9H0E2
PDB IDs		1MHQ	1WGL 2N31
Enriched GO Terms of Interacting Partners?
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