KDM4B and H3-5

Number of citations of the paper that reports this interaction (PubMedID 23455924)
38

Data Source:
BioGRID (two hybrid)

		KDM4B	H3-5
Description		lysine demethylase 4B	H3.5 histone
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Histone Methyltransferase Complex	Nucleosome Nucleus Nuclear Euchromatin
	Molecular Function	Histone Demethylase Activity Histone Demethylase Activity (H3-K9 Specific) Metal Ion Binding Histone Demethylase Activity (H3-K36 Specific)	Protein Binding Nucleosomal DNA Binding Protein Heterodimerization Activity
	Biological Process	Chromatin Remodeling Histone H3-K9 Demethylation Oxidation-reduction Process Histone H3-K36 Demethylation	Positive Regulation Of Cell Growth
Pathways		HDMs demethylate histones Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Granulocyte percentage of myeloid white cells ( 27863252) Lymphocyte percentage of white cells ( 27863252) Monocyte percentage of white cells ( 27863252) Neutrophil percentage of white cells ( 27863252) Periodontitis (CDC/AAP) ( 24024966) Pulse pressure ( 30578418) Systemic lupus erythematosus ( 28714469) Systolic blood pressure ( 30224653) Urate levels ( 31578528)
Interacting Genes		2 interacting genes: H3-5 MED10	12 interacting genes: KAT6A KDM1A KDM4B NASP NSD3 PRMT5 PRMT6 PRMT7 SETMAR SMYD1 SMYD3 SUV39H1
Entrez ID		23030	440093
HPRD ID		11056	18443
Ensembl ID		ENSG00000127663	ENSG00000188375
Uniprot IDs		A0A0C4DFL8 F5GX28 O94953	Q6NXT2
PDB IDs		4LXL 4UC4	2PUY 3KV4 4Z5T 5BWN 5BWO 5F6K 5I3L
Enriched GO Terms of Interacting Partners?
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