KIFAP3 and KIF3B

Number of citations of the paper that reports this interaction (PubMedID 27173435)
49

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, two hybrid, in vivo)

		KIFAP3	KIF3B
Description		kinesin associated protein 3	kinesin family member 3B
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Cell Endoplasmic Reticulum Golgi Apparatus Centrosome Cytosol Spindle Microtubule Cilium Axoneme Microtubule Cytoskeleton Kinesin II Complex Photoreceptor Connecting Cilium Ciliary Transition Zone Ciliary Basal Body Ciliary Tip Periciliary Membrane Compartment	Cell Centrosome Cytosol Kinesin Complex Plus-end Kinesin Complex Microtubule Spindle Microtubule Cilium Microtubule Cytoskeleton Membrane Kinesin II Complex Midbody Extracellular Exosome Ciliary Tip Axon Cytoplasm
	Molecular Function	Protein Binding Kinesin Binding Protein Phosphatase Binding Intraciliary Transport Particle B Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Rho GTPase Binding Intraciliary Transport Particle B Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Process Microtubule-based Movement Signal Transduction Negative Regulation Of Cell Proliferation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Intraciliary Transport Involved In Cilium Assembly Negative Regulation Of Apoptotic Process Cilium Organization Positive Regulation Of Calcium-dependent Cell-cell Adhesion Protein-containing Complex Assembly Plus-end-directed Vesicle Transport Along Microtubule	Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Movement Mitotic Spindle Organization Mitotic Centrosome Separation Determination Of Left/right Symmetry Anterograde Axonal Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Cytokinesis Intraciliary Transport Involved In Cilium Assembly Plus-end-directed Vesicle Transport Along Microtubule Mitotic Spindle Assembly
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane MHC class II antigen presentation Intraflagellar transport COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins	Translocation of SLC2A4 (GLUT4) to the plasma membrane MHC class II antigen presentation Intraflagellar transport COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Amyotrophic lateral sclerosis ( 19451621) Atrial fibrillation ( 28416818) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Age at first sexual intercourse ( 27089180) Chronic obstructive pulmonary disease ( 28166215) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Granulocyte percentage of myeloid white cells ( 27863252) Inflammatory bowel disease ( 28067908) Monocyte percentage of white cells ( 27863252)
Interacting Genes		27 interacting genes: APC AR CCSER2 DHX37 DISC1 GTSE1 KIF3B MAP3K10 MAP3K11 MARK2 MEST MINK1 NAA10 NAV1 NCF2 NIPSNAP3A NUDT21 PARD6G PEX19 PRNP RAP1GDS1 RBFOX1 RBM14 RPGR SMC3 SRC TOR1AIP1	12 interacting genes: APP IFT20 KIF3A KIFAP3 LMO2 LMO4 MAP3K10 MAP3K11 NEDD4L PRC1 RAB4A SASH1
Entrez ID		22920	9371
HPRD ID		03499	04781
Ensembl ID		ENSG00000075945	ENSG00000101350
Uniprot IDs		Q92845	O15066
PDB IDs			3B6U
Enriched GO Terms of Interacting Partners?
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