FKBP4 and SH3BP4

Number of citations of the paper that reports this interaction (PubMedID 18654987)
16

Data Source:
BioGRID (two hybrid)

		FKBP4	SH3BP4
Description		FKBP prolyl isomerase 4	SH3 domain binding protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Cytosol Microtubule Protein-containing Complex Neuronal Cell Body Axonal Growth Cone Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Cytoplasm Clathrin-coated Pit Clathrin-coated Vesicle Extracellular Exosome
	Molecular Function	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding ATP Binding GTP Binding FK506 Binding Protein Binding, Bridging Heat Shock Protein Binding Copper-dependent Protein Binding Glucocorticoid Receptor Binding Tau Protein Binding Phosphoprotein Binding	GDP-dissociation Inhibitor Activity Protein Binding Ras GTPase Binding Identical Protein Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Protein Folding Steroid Hormone Receptor Complex Assembly Copper Ion Transport Embryo Implantation Negative Regulation Of Neuron Projection Development Androgen Receptor Signaling Pathway Prostate Gland Development Negative Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Microtubule Polymerization Protein-containing Complex Localization Male Sex Differentiation Chaperone-mediated Protein Folding Regulation Of Cellular Response To Heat	Endocytosis Negative Regulation Of Cell Proliferation Positive Regulation Of Autophagy Negative Regulation Of Cell Growth Negative Regulation Of TOR Signaling Negative Regulation Of GTPase Activity Amino Acid Import Regulation Of Catalytic Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus
Pathways		HSP90 chaperone cycle for steroid hormone receptors (SHR) Attenuation phase ESR-mediated signaling Estrogen-dependent gene expression	Amino acids regulate mTORC1
Drugs
Diseases
GWAS		FEV1 ( 30804560) Lung function (FVC) ( 30804560) Peak expiratory flow ( 30804560) Quantitative traits ( 19197348)	Depression in smokers ( 30219690) Dialysis-related mortality ( 21546767) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Obstetric antiphospholipid syndrome ( 28424481) Orofacial clefts ( 22419666)
Interacting Genes		26 interacting genes: ACVR1 AHSA1 ATOX1 CALM1 CSNK2A1 EGFR ESR1 FES FKBP1A GLMN HSF1 HSP90AA1 HSPA4 IRF4 NR3C1 NR3C2 PHYH PTPN2 S100A1 S100A2 S100A6 SH3BP4 SMURF2 SNCA SQSTM1 STIP1	22 interacting genes: C2orf73 CCT3 CEP78 CIZ1 DNAJA4 FKBP4 GAPDHS GIPC1 GKAP1 HSPA5 MPHOSPH8 MRGBP NFU1 PLEKHA1 PRR14 PSMA1 TCP1 TTC1 TXNL1 YWHAE YWHAG ZBTB37
Entrez ID		2288	23677
HPRD ID		11794	09285
Ensembl ID		ENSG00000004478	ENSG00000130147
Uniprot IDs		Q02790	Q9P0V3
PDB IDs		1N1A 1P5Q 1Q1C 1QZ2 4DRJ 4LAV 4LAW 4LAX 4LAY 4TW8
Enriched GO Terms of Interacting Partners?
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