RAB11FIP2 and RAB25

Number of citations of the paper that reports this interaction (PubMedID 11495908)
118

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		RAB11FIP2	RAB25
Description		RAB11 family interacting protein 2	RAB25, member RAS oncogene family
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GO Annotations	Cellular Component	Phagocytic Cup Cell Nucleoplasm Endosome Cytoplasmic Vesicle Membrane Cell Projection Intracellular Membrane-bounded Organelle Recycling Endosome Membrane	Endosome Endomembrane System Pseudopodium Pseudopodium Membrane Cytoplasmic Vesicle Recycling Endosome Extracellular Exosome
	Molecular Function	Protein Binding Rab GTPase Binding Protein Kinase Binding Identical Protein Binding Protein Homodimerization Activity	GTPase Activity Protein Binding GTP Binding Myosin V Binding
	Biological Process	Renal Water Homeostasis Phagocytosis Establishment Of Cell Polarity TRAM-dependent Toll-like Receptor 4 Signaling Pathway Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of GTPase Activity Regulated Exocytosis Positive Regulation Of Protein Localization To Plasma Membrane	Epithelial Cell Morphogenesis Intracellular Protein Transport Exocytosis Positive Regulation Of Cell Proliferation Positive Regulation Of Epithelial Cell Migration Pseudopodium Organization Rab Protein Signal Transduction Regulation Of Vesicle-mediated Transport
Pathways		Vasopressin regulates renal water homeostasis via Aquaporins	RAB geranylgeranylation
Drugs
Diseases
GWAS		Age spots ( 29895819) Asthma (sex interaction) ( 24824216) Celiac disease ( 23936387) Freckles ( 29895819) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 30993211 29403010)
Interacting Genes		14 interacting genes: AP2A1 CXCR2 EHD1 ITSN1 LRRK2 MARK2 MYO5B PDZD11 RAB11A RAB11B RAB11FIP4 RAB25 REPS1 YWHAG	13 interacting genes: ACVR1 BMPR1B ITGB1 MED31 MYO5B OPTN RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP5 SMAD4 SMURF2 TGFBR1
Entrez ID		22841	57111
HPRD ID		10548	06698
Ensembl ID		ENSG00000107560	ENSG00000132698
Uniprot IDs		Q7L804	P57735
PDB IDs		2GZD 2GZH 2K6S 3TSO 4C4P	2OIL 3TSO
Enriched GO Terms of Interacting Partners?
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