PHLDA1 and PABPC4

Number of citations of the paper that reports this interaction (PubMedID 11369516)
7

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		PHLDA1	PABPC4
Description		pleckstrin homology like domain family A member 1	poly(A) binding protein cytoplasmic 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Cytoplasmic Vesicle	Nucleus Cytoplasm Cytosol Cytoplasmic Stress Granule Ribonucleoprotein Complex
	Molecular Function	Protein Binding Phosphatidylinositol Phosphate Binding	RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding Poly(C) RNA Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Apoptotic Process Positive Regulation Of Apoptotic Process FasL Biosynthetic Process	RNA Processing RNA Catabolic Process Translation Blood Coagulation Regulation Of MRNA Stability Myeloid Cell Development
Pathways		Interaction between PHLDA1 and AURKA
Drugs
Diseases
GWAS		Anti-thyroid peroxidase (TPOAb) levels in Hashimoto's thyroiditis ( 30926877) Atrial fibrillation ( 30061737 29892015) Blood trace element (Cu levels) ( 23720494) Blood urea nitrogen levels ( 31152163 29403010) Creatinine levels ( 29403010) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Estimated glomerular filtration rate ( 31152163 30604766) Glomerular filtration rate ( 29403010) Glomerular filtration rate (creatinine) ( 26831199) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)	C-reactive protein levels ( 30388399 21300955) C-reactive protein levels or HDL-cholesterol levels (pleiotropy) ( 27286809) C-reactive protein levels or triglyceride levels (pleiotropy) ( 27286809) Chronic obstructive pulmonary disease ( 30804561) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Coffee consumption ( 31046077) Diastolic blood pressure ( 27618448) HDL cholesterol ( 24097068 30275531 25961943 20686565) HDL cholesterol levels ( 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) High density lipoprotein cholesterol levels ( 29615537) Mean arterial pressure ( 27618448) Medication use (drugs used in diabetes) ( 31015401) Metabolic syndrome ( 31589552) Red cell distribution width ( 27863252) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		10 interacting genes: APP EIF3D FBXO7 HSPA4 HSPA4L KRTAP4-12 MDFI PABPC4 PLSCR1 RPL14	23 interacting genes: EEF1A1 FOXD3 GDF9 HAP1 HCRTR1 IL7R LUC7L2 MED31 MKNK1 MTF1 NMNAT1 PHLDA1 PRKCG RIF1 S100A8 SETDB1 SMAD9 SREK1 SRPK2 UBC VPS26B XRN1 ZNF655
Entrez ID		22822	8761
HPRD ID		05625	04557
Ensembl ID		ENSG00000139289	ENSG00000090621
Uniprot IDs		Q8WV24	Q13310
PDB IDs
Enriched GO Terms of Interacting Partners?
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