TFEC and TFEB

Number of citations of the paper that reports this interaction (PubMedID 9806910)
55

Data Source:
HPRD (in vivo)

		TFEC	TFEB
Description		transcription factor EC	transcription factor EB
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm	Nuclear Chromatin Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Protein Dimerization Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Regulatory Region DNA Binding Protein Dimerization Activity
	Biological Process	Cellular Response To Heat Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Nucleic Acid-templated Transcription	Embryonic Placenta Development Adaptive Immune Response Regulation Of Transcription, DNA-templated Autophagy Humoral Immune Response Lysosome Organization Regulation Of Gene Expression Positive Regulation Of Autophagy Lysosome Localization Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Body mass index ( 28892062) Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Height ( 28552196) Intraocular pressure ( 29617998 29785010 29235454) Number of sexual partners ( 30643258) Tonsillectomy ( 27182965 28928442)	Attention deficit hyperactivity disorder ( 18839057) Blood urea nitrogen levels ( 31152163) Colorectal cancer ( 26965516 30529582) Creatinine levels ( 29403010) Estimated glomerular filtration rate ( 31152163 31015462 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Late-onset Alzheimer's disease ( 27770636)
Interacting Genes		8 interacting genes: DCK DEFB127 HNRNPA1 MITF NAPB TFE3 TFEB ZMAT2	4 interacting genes: MITF SRPK1 TFE3 TFEC
Entrez ID		22797	7942
HPRD ID		05294	02847
Ensembl ID		ENSG00000105967	ENSG00000112561
Uniprot IDs		O14948	A0A024RCY3 B0QYS6 P19484
PDB IDs
Enriched GO Terms of Interacting Partners?
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