FAM217A and CLNK

Number of citations of the paper that reports this interaction (PubMedID 25814554)
22

Data Source:
BioGRID (two hybrid)

		FAM217A	CLNK
Description		family with sequence similarity 217 member A	cytokine dependent hematopoietic cell linker
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Protein-containing Complex
	Molecular Function		SH3/SH2 Adaptor Activity Protein Binding Protein-containing Complex Binding
	Biological Process		Positive Regulation Of Natural Killer Cell Cytokine Production Immune Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Cell Death Negative Regulation Of Natural Killer Cell Activation Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS		Night sleep phenotypes ( 27126917)	Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Family history of Alzheimer's disease ( 30617256) Resistance to antihypertensive treatment in hypertension ( 28222112) Rheumatoid arthritis ( 30423114 24390342) Systemic lupus erythematosus ( 28714469) Takayasu arteritis ( 25604533) Urate levels ( 31578528) Uterine fibroid size (maximum dimension) ( 30196971) Vitiligo ( 22561518)
Interacting Genes		1 interacting genes: CLNK	30 interacting genes: ANKRD50 ARAP3 BMX COQ9 CRK CYB561D2 EGFR ERBB2 FAM217A GLIS3 GRB2 GSTCD JAKMIP1 LCP2 NME4 P4HA2 PACSIN3 PIK3R1 PIK3R3 PPP1R7 PTK7 RASSF1 RB1 RPAIN SFMBT1 SMARCD1 SOCS6 STK36 TXK WWOX
Entrez ID		222826	116449
HPRD ID		10789	14720
Ensembl ID		ENSG00000145975	ENSG00000109684
Uniprot IDs		A0A024QZY6 Q8IXS0	Q7Z7G1
PDB IDs
Enriched GO Terms of Interacting Partners?
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