SKA1 and SYCE1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SKA1	SYCE1
Description		spindle and kinetochore associated complex subunit 1	synaptonemal complex central element protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Outer Kinetochore Cytosol Spindle Microtubule Microtubule Cytoskeleton Mitotic Spindle	Synaptonemal Complex Central Element Nucleoplasm Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding
	Biological Process	Mitotic Cell Cycle Chromosome Segregation Regulation Of Microtubule Polymerization Or Depolymerization Cell Division	Synaptonemal Complex Assembly Cell Division
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Meiotic synapsis
Drugs
Diseases
GWAS		Itch intensity from mosquito bite adjusted by bite size ( 28199695) Large HDL particle concentration ( 29084231) Phospholipid levels in large HDL ( 29084231) Phospholipid levels in medium HDL ( 29084231)
Interacting Genes		7 interacting genes: AURKB BLOC1S6 CCDC197 NDC80 SKA2 SPC24 SYCE1	36 interacting genes: ALOX5 ARNT2 BFSP2 CBY2 CCDC102B CINP CNN1 CYTH3 EDRF1 FAM161A HAUS1 HMG20B HOOK1 HSPB1 HSPB7 IQUB KIFC3 KRT18 LMNA MPV17 MRFAP1L1 NME7 PSTPIP1 RBCK1 SCNM1 SKA1 SMARCE1 SSX2 STX19 TFIP11 TPM1 TPM3 TRAF1 TSG101 WASHC3 ZNF124
Entrez ID		220134	93426
HPRD ID		12689	12598
Ensembl ID		ENSG00000154839	ENSG00000171772
Uniprot IDs		A0A024R294 Q96BD8	A0A0B4J1R9 Q8N0S2
PDB IDs		4AJ5 4C9Y 4CA0
Enriched GO Terms of Interacting Partners?
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