ETV6 and L3MBTL1

Number of citations of the paper that reports this interaction (PubMedID 12588862)
44

Data Source:
HPRD (in vitro, in vivo)

		ETV6	L3MBTL1
Description		ETS variant transcription factor 6	L3MBTL histone methyl-lysine binding protein 1
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleolus Cytosol	Chromatin Condensed Chromosome Nucleus Nucleoplasm Nucleolus Plasma Membrane
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Protein Domain Specific Binding	Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Nucleosome Binding Nucleosomal Histone Binding SAM Domain Binding Methylated Histone Binding Histone Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Vitellogenesis Neurogenesis Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Hematopoietic Stem Cell Proliferation Mesenchymal Cell Apoptotic Process	Chromatin Organization Regulation Of Mitotic Nuclear Division Hemopoiesis Regulation Of Megakaryocyte Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Signaling by membrane-tethered fusions of PDGFRA or PDGFRB	Regulation of TP53 Activity through Methylation
Drugs			2-(N-Morpholino)-Ethanesulfonic Acid
Diseases		Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)
GWAS		Asthma ( 27611488) Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Colorectal cancer ( 27145994) Height ( 28552196 20881960 25282103 23563607 31562340 18391951) Night sleep phenotypes ( 27126917) Phosphorus levels ( 29403010)	Antibody level in response to infection ( 25758998) Daytime sleep phenotypes ( 27126917)
Interacting Genes		17 interacting genes: AP1M1 AXIN1 CRKL FBXL6 FLI1 GAB2 GRB2 HDAC9 KAT5 L3MBTL1 NTAQ1 PIN1 SIN3A SMURF1 SUMO1 TRAF2 UBE2I	7 interacting genes: CBX3 ETV6 ETV7 H1-5 H4-16 RB1 SETD7
Entrez ID		2120	26013
HPRD ID		15976	16387
Ensembl ID		ENSG00000139083	ENSG00000185513
Uniprot IDs		A0A0S2Z3C9 P41212	Q9Y468
PDB IDs		1JI7 1LKY 2DAO 2QAR 2QB0 2QB1 5L0P	1OYX 1OZ2 1OZ3 2PQW 2RHI 2RHU 2RHX 2RHY 2RHZ 2RI2 2RI3 2RI5 2RJC 2RJD 2RJE 2RJF 3OQ5 3P8H 3UWN 6BYB
Enriched GO Terms of Interacting Partners?
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