ERCC2 and HERC5

  • Number of citations of the paper that reports this interaction (PubMedID 16884686)
  • 29

ERCC2

HERC5

Description ERCC excision repair 2, TFIIH core complex helicase subunit HECT and RLD domain containing E3 ubiquitin protein ligase 5
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Lung Cancer (DNA repair capacity) ( 23108145)
  • Pulmonary function decline ( 22424883)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 16 interacting genes: AR CDK1 CDK7 ERCC3 ERCC5 GTF2H1 GTF2H2 GTF2H2C_2 GTF2H3 HERC5 MNAT1 MTDH RAD51 RAD52 TP53 TRIM25 14 interacting genes: CCNA2 CCNB1 CCND1 CCNE1 CDKN1A ERCC2 IRF3 MTDH NME2 PITX2 STK38 UBE2D1 UBE2D2 UBE2L6
Entrez ID 2068 51191
HPRD ID 00530 10502
Ensembl ID ENSG00000104884 ENSG00000138646
Uniprot IDs P18074 B4DXV3 Q9UII4
PDB IDs 5IVW 5IY6 5IY7 5IY8 5IY9 5OF4 6NMI 6O9L 6O9M 6RO4
Enriched GO Terms of Interacting Partners?
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