EPHX2 and NIPSNAP3A

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		EPHX2	NIPSNAP3A
Description		epoxide hydrolase 2	nipsnap homolog 3A
Image			No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Matrix Cytosol Extracellular Exosome	Nucleus Mitochondrion Cytosol
	Molecular Function	Magnesium Ion Binding Epoxide Hydrolase Activity Toxic Substance Binding Phosphatase Activity 10-hydroxy-9-(phosphonooxy)octadecanoate Phosphatase Activity Lipid Phosphatase Activity Protein Homodimerization Activity	Protein Binding
	Biological Process	Protein Targeting To Peroxisome Response To Toxic Substance Positive Regulation Of Gene Expression Dephosphorylation Epoxygenase P450 Pathway Cholesterol Homeostasis Long-chain Fatty Acid Biosynthetic Process Stilbene Catabolic Process Phospholipid Dephosphorylation Regulation Of Cholesterol Metabolic Process Epoxide Metabolic Process
Pathways		Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) Biosynthesis of maresins Peroxisomal protein import Peroxisomal protein import
Drugs		N-Cyclohexyl-N'-(4-Iodophenyl)Urea N-Cyclohexyl-N'-Decylurea N-Cyclohexyl-N'-(Propyl)Phenyl Urea N-[(CYCLOHEXYLAMINO)CARBONYL]GLYCINE 4-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}BUTANOIC ACID 6-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEXANOIC ACID 7-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEPTANOIC ACID Ebselen
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder lithium response (categorical) or schizophrenia ( 29121268) Crohn's disease ( 26192919) Dental caries ( 23259602) Inflammatory bowel disease ( 26192919) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Parental longevity (combined parental attained age, Martingale residuals) ( 29227965) Parental longevity (father's attained age) ( 29227965) Schizophrenia ( 25056061 29483656) Smoking behaviour (cigarettes smoked per day) ( 31089300) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032)	HDL cholesterol ( 23505323) Height ( 28552196) Metabolite levels ( 23823483) Response to cytidine analogues (gemcitabine) ( 24483146) vWF levels ( 30586737)
Interacting Genes		5 interacting genes: MTDH MVP NIPSNAP3A PEX5 TERF1	12 interacting genes: CCDC90B CEP70 ELP1 EPHX2 ERP44 FAM219A GOLM1 HAP1 IMMT KIFAP3 SETDB1 TP63
Entrez ID		2053	25934
HPRD ID		00582	16399
Ensembl ID		ENSG00000120915	ENSG00000136783
Uniprot IDs		P34913	Q9UFN0
PDB IDs		1S8O 1VJ5 1ZD2 1ZD3 1ZD4 1ZD5 3ANS 3ANT 3I1Y 3I28 3KOO 3OTQ 3PDC 3WK4 3WK5 3WK6 3WK7 3WK8 3WK9 3WKA 3WKB 3WKC 3WKD 3WKE 4C4X 4C4Y 4C4Z 4HAI 4J03 4JNC 4OCZ 4OD0 4X6X 4X6Y 4Y2J 4Y2P 4Y2Q 4Y2R 4Y2S 4Y2T 4Y2U 4Y2V 4Y2X 4Y2Y 5AHX 5AI0 5AI4 5AI5 5AI6 5AI8 5AI9 5AIA 5AIB 5AIC 5AK3 5AK4 5AK5 5AK6 5AKE 5AKG 5AKH 5AKI 5AKJ 5AKK 5AKL 5AKX 5AKY 5AKZ 5ALD 5ALE 5ALF 5ALG 5ALH 5ALI 5ALJ 5ALK 5ALL 5ALM 5ALN 5ALO 5ALP 5ALQ 5ALR 5ALS 5ALT 5ALU 5ALV 5ALW 5ALX 5ALY 5ALZ 5AM0 5AM1 5AM2 5AM3 5AM4 5AM5 5FP0 5MWA 6AUM 6I5E 6I5G
Enriched GO Terms of Interacting Partners?
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