EPHB6 and DUSP19

Number of citations of the paper that reports this interaction (PubMedID 28065597)
26

Data Source:
BioGRID (two hybrid)

		EPHB6	DUSP19
Description		EPH receptor B6	dual specificity phosphatase 19
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex	Cytoplasm
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Activity Ephrin Receptor Activity ATP Binding Signaling Receptor Activity	Protein Tyrosine Phosphatase Activity Protein Kinase Inhibitor Activity MAP-kinase Scaffold Activity Protein Binding JUN Kinase Phosphatase Activity Protein Kinase Activator Activity Mitogen-activated Protein Kinase Kinase Kinase Binding
	Biological Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Peptidyl-tyrosine Phosphorylation Positive Regulation Of Kinase Activity Ephrin Receptor Signaling Pathway	Negative Regulation Of Protein Kinase Activity Activation Of Protein Kinase Activity Peptidyl-tyrosine Dephosphorylation Regulation Of MAP Kinase Activity Positive Regulation Of MAPK Cascade Positive Regulation Of JUN Kinase Activity Negative Regulation Of JUN Kinase Activity Positive Regulation Of Protein Kinase Activity Negative Regulation Of JNK Cascade Positive Regulation Of JNK Cascade
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 30072576 29875488) Cancer ( 29299148)
Interacting Genes		19 interacting genes: AFDN CBL CRK CRKL DUSP18 DUSP19 EFNB2 EPHB1 ERBB2 GRB2 HDHD2 INCA1 NIF3L1 NOTCH2NLA REL SAT1 STYX TCF4 TRIM39	18 interacting genes: ALK EGFR EPHA2 EPHB6 ERBB2 ERBB3 ERBB4 FLT4 IGF1R INSR KDR LMTK2 MAP2K7 MAP3K5 MAPK9 PTK7 ROR1 ROR2
Entrez ID		2051	142679
HPRD ID		04133	13254
Ensembl ID		ENSG00000106123	ENSG00000162999
Uniprot IDs		F8WCM8 J3KQU5 O15197	Q8WTR2
PDB IDs			3S4E 4D3P 4D3Q 4D3R
Enriched GO Terms of Interacting Partners?
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