EPB41L2 and SPTAN1

Number of citations of the paper that reports this interaction (PubMedID 12044158)
27

Data Source:
HPRD (in vitro)

		EPB41L2	SPTAN1
Description		erythrocyte membrane protein band 4.1 like 2	spectrin alpha, non-erythrocytic 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Spectrin COP9 Signalosome Cell Junction Extracellular Exosome Cell Cortex Region	Extracellular Region Cytosol Spectrin Microtubule Cytoskeleton Membrane Specific Granule Lumen Intracellular Membrane-bounded Organelle Extracellular Exosome Extracellular Vesicle Tertiary Granule Lumen
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding Spectrin Binding PH Domain Binding	Actin Binding Structural Constituent Of Cytoskeleton Calcium Ion Binding Protein Binding Calmodulin Binding Cadherin Binding
	Biological Process	Cell Cycle Cortical Actin Cytoskeleton Organization Actomyosin Structure Organization Cell Division Positive Regulation Of Protein Localization To Cell Cortex	MAPK Cascade ER To Golgi Vesicle-mediated Transport Cytoskeleton Organization Axon Guidance Neutrophil Degranulation Actin Filament Capping
Pathways		Neurexins and neuroligins	Caspase-mediated cleavage of cytoskeletal proteins Nephrin family interactions NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade Neutrophil degranulation COPI-mediated anterograde transport
Drugs
Diseases			Early infantile epileptic encephalopathy; Ohtahara syndrome
GWAS		Cerebellum white matter volume ( 31530798) Colorectal cancer (calcium intake interaction) ( 25192705) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) Lentiform nucleus volume ( 22903471) Loneliness ( 31518406 29970889) Loneliness (MTAG) ( 29970889) Mean corpuscular volume ( 27863252) Pars triangularis volume ( 31530798) Response to statins (LDL cholesterol change) ( 22331829) Systolic blood pressure ( 30224653) Urolithiasis ( 30975718)	Axial length ( 24144296) Body mass index ( 26426971)
Interacting Genes		15 interacting genes: ACTA1 ADORA1 APP ATXN1L DRD1 DRD3 FKBP2 GRIA1 GRM1 HSPB1 NUMA1 SPTAN1 YWHAG YWHAH YWHAZ	56 interacting genes: ABI1 ABL1 ACP1 ACTA1 ACTB AKIP1 ANK1 CAPN1 CASP3 CASP7 CEP63 CNTRL CTNNA1 DDX24 DES EPB41 EPB41L2 EPB42 ERCC4 EVL EXOC1 FANCA FANCC GAP43 GRIA2 GRIN1 GRIN2A GRIN2B GRIN2D KALRN KARS1 MAPK6 NEFL PDE4D PIN4 PLEC PLEKHA5 PRKCB PTEN PTOV1 SHANK1 SHANK3 SLC9A2 SOS1 SPTB SPTBN1 SPTBN2 SPTBN4 SRC STAT1 SYN1 TAF1 TANC1 TES TSSC4 ZNF333
Entrez ID		2037	6709
HPRD ID		09126	01684
Ensembl ID		ENSG00000079819	ENSG00000197694
Uniprot IDs		B4DJ76 I6L9B1 O43491 Q59FD8	A0A384P5S9 Q13813
PDB IDs			2FOT 3F31 3FB2 5FW9 5FWB 5FWC
Enriched GO Terms of Interacting Partners?
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