ENO1 and AGTPBP1

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ENO1	AGTPBP1
Description		enolase 1	ATP/GTP binding protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Phosphopyruvate Hydratase Complex Extracellular Space Nucleus Cytoplasm Cytosol Plasma Membrane Cell Surface Membrane M Band Extracellular Exosome Cell Cortex Region	Nucleus Nucleolus Cytoplasm Mitochondrion Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Magnesium Ion Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific RNA Binding Phosphopyruvate Hydratase Activity Protein Binding Protein Homodimerization Activity Cadherin Binding GTPase Binding	Metallocarboxypeptidase Activity Zinc Ion Binding Tubulin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Gluconeogenesis Response To Virus Positive Regulation Of Plasminogen Activation Negative Regulation Of Cell Growth Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Muscle Contraction Canonical Glycolysis Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of ATP Biosynthetic Process	Eye Photoreceptor Cell Differentiation Proteolysis Mitochondrion Organization Cerebellar Purkinje Cell Differentiation Olfactory Bulb Development Protein Deglutamylation C-terminal Protein Deglutamylation Protein Side Chain Deglutamylation Neuromuscular Process
Pathways		Glycolysis Gluconeogenesis Manipulation of host energy metabolism	Carboxyterminal post-translational modifications of tubulin
Drugs		Zinc Copper Artenimol
Diseases
GWAS		Asthma ( 30929738) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Blood protein levels ( 30072576) Feeling tense ( 29500382) Plateletcrit ( 27863252) Tonsillectomy ( 27182965 28928442) White blood cell count (basophil) ( 27863252)	General risk tolerance (MTAG) ( 30643258)
Interacting Genes		26 interacting genes: AGTPBP1 AMBP BHLHE40 BRCA1 CHEK2 CLK1 FANCA FYN GRB2 HDAC1 HEMGN HSPB2 LIG4 MCPH1 MYOC PCNA PLG SERPING1 SRC SUMO2 SUMO4 TERT TRAPPC2 UPF2 YWHAQ YWHAZ	9 interacting genes: CBY1 CYCS DISC1 ENO1 NYNRIN PPFIA1 PPFIA4 TNIK UBC
Entrez ID		2023	23287
HPRD ID		01400	08442
Ensembl ID		ENSG00000074800	ENSG00000135049
Uniprot IDs		A0A024R4F1 P06733	A0A024R288 J3KNS1 Q9UPW5
PDB IDs		2PSN 3B97 5JLZ 5LAX 5NI9 5NIG 5OCK
Enriched GO Terms of Interacting Partners?
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