ELN and NID2

Number of citations of the paper that reports this interaction (PubMedID 10544250)
18

Data Source:
HPRD (in vitro)

		ELN	NID2
Description		elastin	nidogen 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix Collagen-containing Extracellular Matrix Elastic Fiber	Extracellular Region Basement Membrane Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Constituent Conferring Elasticity Extracellular Matrix Binding	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Collagen Binding
	Biological Process	Outflow Tract Morphogenesis Aortic Valve Morphogenesis Skeletal Muscle Tissue Development Respiratory Gaseous Exchange Blood Circulation Animal Organ Morphogenesis Extracellular Matrix Organization Regulation Of Actin Filament Polymerization Stress Fiber Assembly Regulation Of Smooth Muscle Cell Proliferation	Cell Adhesion Cell-matrix Adhesion Extracellular Matrix Organization Basement Membrane Organization
Pathways		Degradation of the extracellular matrix Elastic fibre formation Molecules associated with elastic fibres Molecules associated with elastic fibres	Laminin interactions Laminin interactions
Drugs		Rofecoxib
Diseases		Congenital supravalvar aortic stenosis Cutis laxa, including: Autosomal dominant cutis laxa (ADCL); Autosomal recessive cutis laxa I (ARCL1); Autosomal recessive cutis laxa II (ARCL2); X-linked recessive cutis laxa (XRCL); Wrinkly skin syndrome
GWAS		Diverticular disease ( 30177863) Height ( 31562340)	Blood protein levels ( 30072576 29875488) Body mass index ( 28892062) Craniofacial microsomia ( 26853712) Lung cancer (smoking interaction) ( 24658283) Pulmonary function ( 17903307) Triglyceride levels ( 29403010) Waist-to-hip ratio adjusted for body mass index ( 26785701)
Interacting Genes		22 interacting genes: ASS1 BGN CKMT2 CLU DCN ELANE FBLN1 FBLN2 FBN1 FBN2 FCN1 FKBP10 LGALS3 LOX LOXL1 LYZ MAGEH1 MFAP2 MTDH NID2 PRTN3 SPINK1	8 interacting genes: COL13A1 COL1A1 COL4A1 ELN HSPG2 KRTAP10-3 LAMC1 SKIL
Entrez ID		2006	22795
HPRD ID		00556	05654
Ensembl ID		ENSG00000049540	ENSG00000087303
Uniprot IDs		B3KRT8 B4E3S4 E7EN65 E7ENM0 G3V0G6 G5E950 P15502 Q59H17 Q6ZUN2 Q8NBI4	Q14112
PDB IDs
Enriched GO Terms of Interacting Partners?
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