MLKL and THOC3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

		MLKL	THOC3
Description		mixed lineage kinase domain like pseudokinase	THO complex 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane	Transcription Export Complex THO Complex Part Of Transcription Export Complex Nuclear Chromosome, Telomeric Region Nucleoplasm Nuclear Speck
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Protein-containing Complex Binding	RNA Binding
	Biological Process	Protein Phosphorylation Cell Surface Receptor Signaling Pathway Protein Homotrimerization Necroptotic Process	RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Viral MRNA Export From Host Cell Nucleus
Pathways		TRP channels RIPK1-mediated regulated necrosis	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Testicular germ cell tumor ( 23666239)	Chronotype ( 30696823)
Interacting Genes		5 interacting genes: ANAPC11 CDK1 NDUFB7 RAD18 THOC3	4 interacting genes: BRCA1 DDX39B MLKL TK1
Entrez ID		197259	84321
HPRD ID		08752	09497
Ensembl ID		ENSG00000168404	ENSG00000051596
Uniprot IDs		Q8NB16	Q96J01
PDB IDs		2MSV 4M67 4MWI 5KNJ 5KO1 6BWK 6D74
Enriched GO Terms of Interacting Partners?
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