AHR and IVNS1ABP

Number of citations of the paper that reports this interaction (PubMedID 16582008)
7

Data Source:
BioGRID (two hybrid)

		AHR	IVNS1ABP
Description		aryl hydrocarbon receptor	influenza virus NS1A binding protein
Image
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Cytosol Protein-containing Complex Cytosolic Aryl Hydrocarbon Receptor Complex	Nucleoplasm Transcription Factor Complex Spliceosomal Complex Cytosol Cytoskeleton
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific TFIID-class Transcription Factor Complex Binding Transcription Coactivator Binding DNA Binding DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Transcription Factor Binding TBP-class Protein Binding Enhancer Binding Protein Homodimerization Activity Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity Hsp90 Protein Binding E-box Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Blood Vessel Development Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Xenobiotic Metabolic Process Apoptotic Process Cell Cycle Response To Xenobiotic Stimulus Response To Toxic Substance Regulation Of Gene Expression CAMP-mediated Signaling Intracellular Receptor Signaling Pathway Regulation Of B Cell Proliferation Circadian Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To CAMP Cellular Response To Forskolin Cellular Response To 2,3,7,8-tetrachlorodibenzodioxine	Transcription By RNA Polymerase III RNA Splicing Response To Virus Viral Process Negative Regulation Of Protein Ubiquitination Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		PPARA activates gene expression Phase I - Functionalization of compounds Endogenous sterols Xenobiotics Aryl hydrocarbon receptor signalling
Drugs		Omeprazole Mexiletine Nimodipine Flutamide Atorvastatin Leflunomide Ginseng Indirubin-3'-Monoxime Resveratrol Quercetin beta-Naphthoflavone Emodin BENZOTHIAZOLE Diosmin Indigotindisulfonic Acid Kynurenic Acid Epigallocatechin Gallate Cantharidin Indirubin
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Bitter beverage consumption ( 31046077) Bitter non-alcoholic beverage consumption ( 31046077) Blood metabolite levels ( 24816252) Caffeine consumption ( 21490707) Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Coffee consumption ( 31345160 21357676 29367735 31046077 25288136) Coffee consumption (cups per day) ( 25288136) Cutaneous squamous cell carcinoma ( 27424798) Estimated glomerular filtration rate ( 31152163) Inflammatory bowel disease ( 26192919) Lung cancer in ever smokers ( 28604730) Metabolic traits ( 21886157) Microalbuminuria ( 31511532) Plasma kynurenine levels in major depressive disorder ( 29317604) Rosacea symptom severity ( 29771307) Severe influenza A (H1N1) infection ( 26379185) Sweet beverage consumption ( 31046077) Tea consumption ( 31046077) Ulcerative colitis ( 26192919) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 30910378 31511532) Urinary potassium excretion ( 31409800) Urinary sodium excretion ( 31409800)	Lead levels ( 26025379)
Interacting Genes		35 interacting genes: AIP AR ARNT ARNT2 ARNTL BRCA1 CCNT1 CUL4B DAP3 EP300 ESR1 GTF2F1 GTF2F2 HSP90AA1 IVNS1ABP NCOA1 NCOA2 NCOA7 NCOR2 NEDD8 NR2F1 NRIP1 PTGES3 RB1 RELA SMARCA4 SP1 STUB1 TAF4 TAF6 TAF7 TAF9 TBL3 TBP XPO1	10 interacting genes: AHR CHD3 KLHL20 PFN2 RPL6 SYNCRIP TRA2B TRIM14 VIM ZNRD1
Entrez ID		196	10625
HPRD ID		02596	10004
Ensembl ID		ENSG00000106546	ENSG00000116679
Uniprot IDs		A0A024R9Z8 P35869	Q9Y6Y0
PDB IDs		5NJ8	5YY8 6N34 6N3H
Enriched GO Terms of Interacting Partners?
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