CELSR3 and SWAP70

Number of citations of the paper that reports this interaction (PubMedID 12421765)
39

Data Source:
HPRD (two hybrid)

		CELSR3	SWAP70
Description		cadherin EGF LAG seven-pass G-type receptor 3	switching B cell complex subunit SWAP70
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Cell Nucleus Cytoplasm Plasma Membrane Actin Cytoskeleton Lamellipodium
	Molecular Function	G Protein-coupled Receptor Activity Calcium Ion Binding Protein Binding	DNA Binding Calcium Ion Binding Protein Binding ATP Binding Cadherin Binding
	Biological Process	Neuron Migration Regulation Of Protein Phosphorylation Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules G Protein-coupled Receptor Signaling Pathway Axonal Fasciculation Regulation Of Protein Localization Dopaminergic Neuron Axon Guidance Serotonergic Neuron Axon Guidance Wnt Signaling Pathway, Planar Cell Polarity Pathway Cilium Assembly Cell-cell Adhesion Planar Cell Polarity Pathway Involved In Axon Guidance	Positive Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Actin Filament Depolymerization Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Protein Localization Negative Regulation Of Cell-cell Adhesion Mediated By Integrin Isotype Switching Actin Filament Bundle Assembly Positive Regulation Of Mast Cell Chemotaxis Negative Regulation Of Peptidyl-serine Dephosphorylation
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Cognitive ability (MTAG) ( 29186694) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Mental health study participation (provided email address) ( 31263887) Ulcerative colitis ( 28067908)	Blood protein levels ( 30072576 29875488) Coronary artery disease ( 29212778 30104761 26343387) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Diastolic blood pressure ( 30224653 27841878 28739976 30487518) High light scatter reticulocyte percentage of red cells ( 27863252) Hypertension ( 30487518) Ischemic stroke ( 29531354) Mean arterial pressure ( 29403010 30487518) Mean corpuscular hemoglobin concentration ( 27863252) Mean corpuscular volume ( 29403010) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (diuretics) ( 31015401) Platelet distribution width ( 27863252) Pulse pressure ( 27841878) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Systolic blood pressure ( 27841878 30487518 30578418)
Interacting Genes		12 interacting genes: CLK1 CLUH DST IFT140 SCAPER SGSM2 SPTBN2 SPTBN4 SWAP70 TRIP12 TSPYL4 UACA	5 interacting genes: CELSR3 IGHG1 PARP1 RAPGEF4 ZBTB5
Entrez ID		1951	23075
HPRD ID		09179	10378
Ensembl ID		ENSG00000008300	ENSG00000133789
Uniprot IDs		Q9NYQ7	B3KUB9 E7EMB1 Q9UH65
PDB IDs			2DN6
Enriched GO Terms of Interacting Partners?
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