EEF1D and GARS1

Number of citations of the paper that reports this interaction (PubMedID 11829477)
12

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		EEF1D	GARS1
Description		eukaryotic translation elongation factor 1 delta	glycyl-tRNA synthetase 1
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GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Eukaryotic Translation Elongation Factor 1 Complex	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Secretory Granule Axon Extracellular Exosome
	Molecular Function	DNA Binding Translation Elongation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Factor Activity, RNA Binding Cadherin Binding	Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) Activity Glycine-tRNA Ligase Activity Protein Binding ATP Binding Transferase Activity Identical Protein Binding Protein Dimerization Activity
	Biological Process	Translational Elongation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cellular Response To Ionizing Radiation	TRNA Aminoacylation For Protein Translation Glycyl-tRNA Aminoacylation Diadenosine Tetraphosphate Biosynthetic Process Mitochondrial Glycyl-tRNA Aminoacylation
Pathways		Eukaryotic Translation Elongation	Cytosolic tRNA aminoacylation Mitochondrial tRNA aminoacylation
Drugs			Glycine
Diseases			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy Distal hereditary motor neuropathies (dHMN)
GWAS		Schizophrenia ( 31268507)
Interacting Genes		38 interacting genes: APP ARHGAP21 ASCC2 ATG7 CAMSAP2 CD48 CDK1 CDK9 CRMP1 CSNK2A1 CTBP1 CTBP2 ECH1 EEF1G EPRS1 ERP27 FOS FRA10AC1 GARS1 HEXD HSF1 KARS1 KTN1 MAP1B NR2F1 POT1 PRKCA RELA RNF40 RPS6KA1 SIAH1 SIAH2 SQSTM1 TERF1 TINF2 TPT1 UBE2A VARS1	9 interacting genes: CD44 CELSR2 EEF1D HSPB2 IARS1 MAP3K10 MAPK8 NAE1 NEDD8
Entrez ID		1936	2617
HPRD ID		00560	02617
Ensembl ID		ENSG00000104529	ENSG00000106105
Uniprot IDs		B2RAR6 D3DWK1 P29692	A0A090N8G0 P41250
PDB IDs		2MVM 2MVN 2N51 5JPO	2PME 2PMF 2Q5H 2Q5I 2ZT5 2ZT6 2ZT7 2ZT8 2ZXF 4KQE 4KR2 4KR3 4QEI 5E6M
Enriched GO Terms of Interacting Partners?
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