EEF1B2 and TIMP1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		EEF1B2	TIMP1
Description		eukaryotic translation elongation factor 1 beta 2	TIMP metallopeptidase inhibitor 1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Eukaryotic Translation Elongation Factor 1 Complex	Extracellular Region Basement Membrane Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Platelet Alpha Granule Lumen Extracellular Exosome
	Molecular Function	Translation Elongation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protease Binding Cytokine Activity Protein Binding Growth Factor Activity Metalloendopeptidase Inhibitor Activity Zinc Ion Binding Peptidase Inhibitor Activity
	Biological Process	Translational Elongation Response To Ethanol	Cell Activation Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Platelet Degranulation Aging Positive Regulation Of Cell Proliferation Response To Hormone Response To Organic Substance Negative Regulation Of Endopeptidase Activity Cytokine-mediated Signaling Pathway Extracellular Matrix Disassembly Response To Cytokine Negative Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Response To Peptide Hormone Post-translational Protein Modification Cellular Protein Metabolic Process Negative Regulation Of Membrane Protein Ectodomain Proteolysis Cartilage Development Negative Regulation Of Trophoblast Cell Migration Negative Regulation Of Metallopeptidase Activity Regulation Of Integrin-mediated Signaling Pathway
Pathways		Eukaryotic Translation Elongation	Platelet degranulation Activation of Matrix Metalloproteinases Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Interleukin-10 signaling Interleukin-4 and Interleukin-13 signaling Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Body mass index ( 26426971)
Interacting Genes		12 interacting genes: AARS1 APP CSNK2A1 CSNK2A2 DRD3 EEF1G HARS1 TIMP1 TPT1 ULK2 VHL WBP2	9 interacting genes: CD63 ECH1 EEF1B2 MMP1 MMP14 MMP2 MMP3 MYOC RECQL5
Entrez ID		1933	7076
HPRD ID		02804	02371
Ensembl ID		ENSG00000114942	ENSG00000102265
Uniprot IDs		A0A024R3W7 P24534	B4DJK3 P01033 Q6FGX5
PDB IDs		1B64 5DQS	1D2B 1LQN 1OO9 1UEA 2J0T 3MA2 3V96 6MAV 6N9D
Enriched GO Terms of Interacting Partners?
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