ECT2 and POMP

Number of citations of the paper that reports this interaction (PubMedID 22990118)
46

Data Source:
BioGRID (two hybrid)

		ECT2	POMP
Description		epithelial cell transforming 2	proteasome maturation protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cell-cell Junction Bicellular Tight Junction Nuclear Body Midbody Cleavage Furrow Mitotic Spindle Centralspindlin Complex	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Nuclear Speck Organelle Membrane
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Mitotic Cytokinesis Cell Morphogenesis G Protein-coupled Receptor Signaling Pathway Protein Transport Activation Of Protein Kinase Activity Positive Regulation Of Cytokinesis Intracellular Signal Transduction Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of GTPase Activity Positive Regulation Of Neuron Differentiation Regulation Of Protein Kinase Activity Regulation Of Small GTPase Mediated Signal Transduction Protein Homooligomerization Regulation Of Attachment Of Spindle Microtubules To Kinetochore Cellular Response To Hydrogen Peroxide Bicellular Tight Junction Assembly Cellular Response To Calcium Ion Cellular Response To Ionizing Radiation Activation Of GTPase Activity Regulation Of Cytokinesis, Actomyosin Contractile Ring Assembly	Proteasome Assembly
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
Drugs
Diseases			Keratosis linearis with ichthyosis congenita and sclerosing keratoderma; KLICK syndrome
GWAS		Obesity-related traits ( 23251661)	Breast cancer (menopausal hormone therapy interaction) ( 24080446) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252)
Interacting Genes		37 interacting genes: ABR C2orf42 CCDC91 CD19 CDK1 CHST10 CSTB EIF4A2 EIF5B ELOC ERAL1 F2RL2 FANCM GGN ILVBL KLHL20 MBD1 MT-CO2 MT2A NOMO1 NPC2 OOSP2 OTUB1 PARD6A PCOLCE PLK1 POMP PSMA6 RACGAP1 RHOG RPS20 SNRNP200 SPATA22 SRPK2 THAP11 UBB VDAC2	13 interacting genes: ECT2 FAM107A GRB2 KCNA10 PSMA1 PSMA3 PSMB1 PSMB10 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9
Entrez ID		1894	51371
HPRD ID		11860	12613
Ensembl ID		ENSG00000114346	ENSG00000132963
Uniprot IDs		Q9H8V3	Q9Y244
PDB IDs		3L46 4N40
Enriched GO Terms of Interacting Partners?
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