EBF1 and ERO1A

Number of citations of the paper that reports this interaction (PubMedID 27107012)
28

Data Source:
BioGRID (two hybrid)

		EBF1	ERO1A
Description		EBF transcription factor 1	endoplasmic reticulum oxidoreductase 1 alpha
Image
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Cell Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Dendrite Intracellular Membrane-bounded Organelle
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Metal Ion Binding Protein Dimerization Activity C2H2 Zinc Finger Domain Binding	Protein Disulfide Isomerase Activity Protein Binding Protein Disulfide Oxidoreductase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, Disulfide As Acceptor
	Biological Process	Multicellular Organism Development Positive Regulation Of Transcription By RNA Polymerase II	Protein Folding Cellular Protein Modification Process Response To Temperature Stimulus Animal Organ Senescence Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Protein Maturation By Protein Folding Extracellular Matrix Organization Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Oxidative Stress Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis Brown Fat Cell Differentiation Chaperone Cofactor-dependent Protein Refolding Release Of Sequestered Calcium Ion Into Cytosol Oxidation-reduction Process Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia
Pathways		Transcriptional regulation of white adipocyte differentiation	Insulin processing Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs) ( 23648065) Anorexia nervosa (excluding migration to or from binge-eating disorder or bulimia nervosa) ( 28630421) Birth weight ( 31043758 27680694) Blood pressure ( 21909110) Blood protein levels ( 29875488) Breast cancer ( 29059683 23535729 23535733) Carotid intima media thickness ( 26343869) Cognitive decline rate in late mild cognitive impairment ( 26252872) Creatine kinase levels ( 29403010) Diastolic blood pressure ( 28135244 27841878 21909115 28739976 27618452) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) General risk tolerance (MTAG) ( 30643258) Gestational age at birth (maternal effect) ( 28877031) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Heel bone mineral density ( 30598549) Hip circumference (psychosocial stress interaction) ( 25271088) Hypertension ( 21909115 30487518) Hypospadias ( 25108383) Inflammatory skin disease ( 25574825) Longevity (85 years and older) ( 24688116) Longevity (90 years and older) ( 24688116) Lymphocyte percentage of white cells ( 27863252) Male-pattern baldness ( 29146897 27182965 28196072) Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Monocyte percentage of white cells ( 27863252) Non-albumin protein levels ( 29403010) Obesity-related traits ( 23251661) Offspring birth weight ( 31043758) Pericardial adipose tissue adjusted for height and weight ( 27918534) Pericardial fat ( 27918534) Post bronchodilator FEV1 ( 26634245) Preterm birth (maternal effect) ( 28877031) Pulse pressure ( 30224653 28135244 27841878 28739976 30578418) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Systolic blood pressure ( 26390057 28135244 27841878 21909115 28739976 27618452 30578418) Systolic blood pressure (cigarette smoking interaction) ( 29455858) Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Triglyceride levels ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Type 2 diabetes (adjusted for BMI) ( 30297969)	Heel bone mineral density ( 30598549)
Interacting Genes		8 interacting genes: ATPAF2 CREBBP ERO1A HOMEZ MTNR1B PAX5 ZNF423 ZNF521	10 interacting genes: APPBP2 EBF1 ERP44 GPX7 GPX8 P4HB PDIA3 PDILT PELI2 RHOU
Entrez ID		1879	30001
HPRD ID		01256	13278
Ensembl ID		ENSG00000164330	ENSG00000197930
Uniprot IDs		B4E2U8 Q9UH73	Q96HE7
PDB IDs		3LYR 3MQI	3AHQ 3AHR
Enriched GO Terms of Interacting Partners?
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