DPYS and DPYSL5

Number of citations of the paper that reports this interaction (PubMedID 10956643)
46

Data Source:
HPRD (in vivo, two hybrid)

		DPYS	DPYSL5
Description		dihydropyrimidinase	dihydropyrimidinase like 5
Image
GO Annotations	Cellular Component	Cytosol Protein-containing Complex Extracellular Exosome	Cytosol Dendrite Neuronal Cell Body
	Molecular Function	Uracil Binding Thymine Binding Dihydropyrimidinase Activity Zinc Ion Binding Amino Acid Binding Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Cyclic Amides Identical Protein Binding Phosphoprotein Binding	Dihydropyrimidinase Activity Protein Binding Microtubule Binding Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Cyclic Amides
	Biological Process	Pyrimidine Nucleobase Catabolic Process Thymine Catabolic Process Uracil Catabolic Process Beta-alanine Metabolic Process Pyrimidine Nucleoside Catabolic Process	Pyrimidine Nucleobase Catabolic Process Signal Transduction Nervous System Development Axon Guidance
Pathways		Pyrimidine catabolism	CRMPs in Sema3A signaling
Drugs
Diseases		Dihydropyrimidinase deficiency; Dihydropyrimidinuria
GWAS		Irritable mood ( 29500382)	Fasting blood glucose ( 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Obesity-related traits ( 23251661) Reflection (response to stress) ( 30886212) Urate levels ( 31578528) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		1 interacting genes: DPYSL5	9 interacting genes: APPL1 DARS2 DPYS DPYSL2 DPYSL3 DPYSL4 FBN2 FES HSPA5
Entrez ID		1807	56896
HPRD ID		01960	10522
Ensembl ID		ENSG00000147647	ENSG00000157851
Uniprot IDs		Q14117	Q9BPU6
PDB IDs		2VR2	4B90 4B91 4B92
Enriched GO Terms of Interacting Partners?
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