DPAGT1 and MFSD3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		DPAGT1	MFSD3
Description		dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	major facilitator superfamily domain containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Intracellular Membrane-bounded Organelle	Integral Component Of Membrane
	Molecular Function	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase Activity UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase Activity Phospho-N-acetylmuramoyl-pentapeptide-transferase Activity Transferase Activity, Transferring Glycosyl Groups Identical Protein Binding Metal Ion Binding	Solute:proton Symporter Activity
	Biological Process	UDP-N-acetylglucosamine Metabolic Process Protein N-linked Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process Dolichyl Diphosphate Biosynthetic Process Dolichol Metabolic Process	Proton Transmembrane Transport
Pathways		Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2
Drugs
Diseases		Congenital disorders of glycosylation (CDG) type I
GWAS		Estimated glomerular filtration rate ( 31152163)	Blood metabolite levels ( 26401656) Educational attainment ( 25201988)
Interacting Genes		3 interacting genes: LSM8 MFSD3 THTPA	4 interacting genes: APPBP2 DPAGT1 MDFI PCDHGC3
Entrez ID		1798	113655
HPRD ID		01879	14003
Ensembl ID		ENSG00000172269	ENSG00000167700
Uniprot IDs		A0A024R3H8 Q9H3H5	Q96ES6
PDB IDs		5LEV 5O5E 6BW5 6BW6 6FM9 6FWZ
Enriched GO Terms of Interacting Partners?
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