DYNC1I1 and NAGK

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		DYNC1I1	NAGK
Description		dynein cytoplasmic 1 intermediate chain 1	N-acetylglucosamine kinase
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Cell Nucleus Cytoplasm Cytosol Cytoplasmic Dynein Complex Microtubule Vesicle Cytoplasmic Ribonucleoprotein Granule Perinuclear Region Of Cytoplasm Recycling Endosome	Cytosol Extracellular Exosome
	Molecular Function	Motor Activity Microtubule Motor Activity Protein Binding Microtubule Binding Spectrin Binding Dynein Light Chain Binding Dynein Heavy Chain Binding	Protein Binding ATP Binding N-acetylglucosamine Kinase Activity
	Biological Process	ER To Golgi Vesicle-mediated Transport Microtubule-based Movement Transport Along Microtubule Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Vesicle Transport Along Microtubule Positive Regulation Of ATP-dependent Microtubule Motor Activity, Plus-end-directed	N-acetylglucosamine Metabolic Process UDP-N-acetylglucosamine Biosynthetic Process N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process Carbohydrate Phosphorylation
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation	Synthesis of UDP-N-acetyl-glucosamine
Drugs			N-Acetylglucosamine
Diseases
GWAS		Dementia and core Alzheimer's disease neuropathologic changes ( 25188341) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 28552196) Immune reponse to smallpox (secreted IL-10) ( 22610502) Knee osteoarthritis ( 27696742) Multisite chronic pain ( 31194737) Obesity-related traits ( 23251661)	Blood protein levels ( 30072576 29875488 28240269) Erythema nodosum in inflammatory bowel disease ( 24487271)
Interacting Genes		32 interacting genes: ANXA7 BICD1 CADM4 CDKN1A DNM2 DYNLL1 DYNLL2 DYNLRB1 DYNLT1 DYNLT3 EMILIN1 FAM110A FAM83D FBP1 GRB7 GSK3B KAT7 MCC NAGK NDEL1 NUDT21 NUP214 PIN1 RAP1GAP RCC1 RUNDC3B SMN1 STAU1 TAOK1 TK1 TRIM58 WDCP	32 interacting genes: ACTR10 CCDC158 CDKN2C CEP43 DACH1 DCP2 DYNC1I1 GNPNAT1 LACTB2 LENG1 LMO1 LNX1 LNX2 LSM8 MEOX1 MTHFD2 NTAQ1 PJA1 PKM PPHLN1 REL SDCBP SF3B3 SMAD2 SMAD9 SPRED1 SRPK2 STK16 SYNE4 TCF12 TNNT1 WDR82
Entrez ID		1780	55577
HPRD ID		04798	08441
Ensembl ID		ENSG00000158560	ENSG00000124357
Uniprot IDs		A4D1I7 O14576 Q8N542	A0A384N6G7 C9JEV6 Q9UJ70
PDB IDs			2CH5 2CH6
Enriched GO Terms of Interacting Partners?
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