DIAPH2 and NCKIPSD

Number of citations of the paper that reports this interaction (PubMedID 11509578)
28

Data Source:
HPRD (in vivo, in vitro)

		DIAPH2	NCKIPSD
Description		diaphanous related formin 2	NCK interacting protein with SH3 domain
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Early Endosome Endoplasmic Reticulum Cytosol Intracellular Membrane-bounded Organelle	Cytosol Intermediate Filament COP9 Signalosome
	Molecular Function	Actin Binding Signaling Receptor Binding Rho GTPase Binding	Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding
	Biological Process	Actin Filament Organization Multicellular Organism Development Female Gamete Generation Oogenesis	Cytoskeleton Organization Positive Regulation Of Neuron Projection Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Pathways			Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS			Anorexia nervosa ( 31308545) Blood protein levels ( 28240269) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Intelligence (MTAG) ( 29326435) Parkinson's disease ( 28892059) Ulcerative colitis ( 28067908)
Interacting Genes		6 interacting genes: APBB1 CDC42 CENPA NCKIPSD RHOD TCERG1	20 interacting genes: ARHGEF7 BAIAP2 DIAPH2 DIAPH3 DLG4 DMRTB1 FASLG GRB2 HSPB1 ITGB1 KHDRBS1 MAPK3 NCK1 NCK2 PSMD9 SORBS3 STAC WAS WASL YWHAG
Entrez ID		1730	51517
HPRD ID		02117	09450
Ensembl ID		ENSG00000147202	ENSG00000213672
Uniprot IDs		O60879	Q9NZQ3
PDB IDs			6DEC 6DED 6DEE
Enriched GO Terms of Interacting Partners?
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