DDX10 and PTS

		DDX10	PTS
Description		DEAD-box helicase 10	6-pyruvoyltetrahydropterin synthase
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GO Annotations	Cellular Component	Nucleus	Cytoplasm Mitochondrion Cytosol
	Molecular Function	RNA Binding RNA Helicase Activity ATP Binding	6-pyruvoyltetrahydropterin Synthase Activity Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	RRNA Processing Anterior Head Development	Cellular Amino Acid Metabolic Process Tetrahydrobiopterin Biosynthetic Process Central Nervous System Development Cofactor Metabolic Process
Pathways			Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Drugs			Biopterin
Diseases			Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient
GWAS		Knee osteoarthritis ( 28916551) Systolic blood pressure ( 27841878)	Heel bone mineral density ( 30598549) Objective response to lithium treatment ( 26503763)
Interacting Genes		16 interacting genes: ANTXR2 APP ARHGAP20 ARL2BP BCO2 CUL5 DES DSC3 FBXO7 HSPB2 IGFBP6 NPAT PGR PTS SIRPA SLN	10 interacting genes: COIL DDX10 FNDC5 FXR2 LNX1 NTAQ1 PBRM1 PRKG2 SDCBP THAP10
Entrez ID		1662	5805
HPRD ID		03138	11840
Ensembl ID		ENSG00000178105	ENSG00000150787
Uniprot IDs		Q13206	Q03393
PDB IDs		2PL3	3I2B
Enriched GO Terms of Interacting Partners?
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