DBH and PRADC1

Number of citations of the paper that reports this interaction (PubMedID 15498570)
7

Data Source:
HPRD (in vitro)

		DBH	PRADC1
Description		dopamine beta-hydroxylase	protease associated domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Endoplasmic Reticulum Membrane Integral Component Of Membrane Transport Vesicle Membrane Secretory Granule Membrane Centriolar Satellite Chromaffin Granule Lumen Secretory Granule Lumen Chromaffin Granule Membrane Intracellular Membrane-bounded Organelle Synapse	Extracellular Region
	Molecular Function	Catalytic Activity Dopamine Beta-monooxygenase Activity Copper Ion Binding Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Ascorbate As One Donor, And Incorporation Of One Atom Of Oxygen L-ascorbic Acid Binding	Protein Binding
	Biological Process	Cytokine Production Blood Vessel Remodeling Response To Amphetamine Leukocyte Mediated Immunity Octopamine Biosynthetic Process Chemical Synaptic Transmission Memory Locomotory Behavior Visual Learning Regulation Of Cell Proliferation Homoiothermy Dopamine Catabolic Process Norepinephrine Biosynthetic Process Catecholamine Biosynthetic Process Glucose Homeostasis Fear Response Maternal Behavior Positive Regulation Of Vasoconstriction Behavioral Response To Ethanol Response To Pain Leukocyte Migration Oxidation-reduction Process Positive Regulation Of Cold-induced Thermogenesis Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Catecholamine biosynthesis
Drugs		Vitamin C Disulfiram Dopamine
Diseases		Dopamine beta-hydroxylase deficiency; Norepinephrine deficiency; Noradrenaline deficiency
GWAS		Diastolic blood pressure ( 28739976 27618452) Mean arterial pressure ( 27618448) Nicotine dependence ( 28972577) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Smoking behavior ( 20418890) Smoking behaviour (cigarette pack-years) ( 30679032) Smoking behaviour (cigarettes smoked per day) ( 30679032) Smoking cessation ( 30617275) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 27618452 30578418)
Interacting Genes		1 interacting genes: PRADC1	3 interacting genes: DBH VAC14 XRN1
Entrez ID		1621	84279
HPRD ID		01963	12815
Ensembl ID		ENSG00000123454	ENSG00000135617
Uniprot IDs		P09172	Q9BSG0
PDB IDs		4ZEL
Enriched GO Terms of Interacting Partners?
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