ADRB3 and UBXN8

		ADRB3	UBXN8
Description		adrenoceptor beta 3	UBX domain protein 8
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex	Nucleoplasm Nucleolus Endoplasmic Reticulum Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Adrenergic Receptor Activity Beta-adrenergic Receptor Activity Protein Binding Beta3-adrenergic Receptor Activity Protein Homodimerization Activity Epinephrine Binding Norepinephrine Binding	Protein Binding
	Biological Process	Temperature Homeostasis Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Desensitization Of G Protein-coupled Receptor Signaling Pathway By Arrestin Carbohydrate Metabolic Process Generation Of Precursor Metabolites And Energy Energy Reserve Metabolic Process Receptor-mediated Endocytosis G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Cell-cell Signaling Behavior Positive Regulation Of MAPK Cascade Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis	Single Fertilization Ubiquitin-dependent ERAD Pathway
Pathways		Adrenoceptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs		Amphetamine Bethanidine Amitriptyline Olanzapine Norepinephrine Nortriptyline Propranolol Epinephrine Trimipramine Alprenolol Terbutaline Salmeterol Pindolol Formoterol Salbutamol Isoprenaline Arbutamine Fenoterol Ephedra Mephentermine Clenbuterol Oxprenolol Amibegron Solabegron Droxidopa Bufuralol Bopindolol Bupranolol Mirabegron
Diseases
GWAS
Interacting Genes		4 interacting genes: ADRB2 GNAS SRC UBXN8	6 interacting genes: ADRB3 C8orf86 DCTN6 RBPMS SFRP1 WRN
Entrez ID		155	7993
HPRD ID		00188	03692
Ensembl ID		ENSG00000188778	ENSG00000104691
Uniprot IDs		A8KAG8 P13945	B4DKK1 O00124
PDB IDs		2CDW
Enriched GO Terms of Interacting Partners?
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