SH3RF2 and HOMEZ

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SH3RF2	HOMEZ
Description		SH3 domain containing ring finger 2	homeobox and leucine zipper encoding
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nuclear Chromatin Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding Phosphatase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity
	Biological Process	Negative Regulation Of Phosphatase Activity Positive Regulation Of Cell Migration Negative Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Apoptotic Process Negative Regulation Of JNK Cascade Positive Regulation Of JNK Cascade Protein Autoubiquitination	Negative Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Bacteremia ( 27236921) Response to (pegylated) interferon in HBeAG-positive hepatitis B ( 30715261)	Height ( 31562340) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		15 interacting genes: AMOTL2 APP BANP CBY2 FASLG GOLGA2 HOMEZ LMNA LZTS2 MTUS2 PAK4 PPP1CA PPP1CC RBPMS UBE2N	37 interacting genes: AEN AXIN1 CENPS DEF6 DGCR6 DNTTIP1 EBF1 EIF4E2 ELOA GRB2 HOXC8 KPNA2 LNX1 LRRC7 MAD2L1BP MED18 MRPL11 NCK1 NCK2 PIN1 PRKAA1 PRKAA2 RBM39 RNF8 RPGR RPL9 SDCBP SH3RF2 SMARCB1 SMYD1 SNRPB2 SUMO2 TEAD4 TLE5 TRAF4 ZBTB7A ZNF688
Entrez ID		153769	57594
HPRD ID		10229	12167
Ensembl ID		ENSG00000156463	ENSG00000215271
Uniprot IDs		Q08AM8 Q8TEC5	Q8IX15
PDB IDs			2ECC 2YS9
Enriched GO Terms of Interacting Partners?
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