JAKMIP1 and NKX2-1

		JAKMIP1	NKX2-1
Description		janus kinase and microtubule interacting protein 1	NK2 homeobox 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Extrinsic Component Of Membrane Ribonucleoprotein Complex	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex
	Molecular Function	RNA Binding Protein Binding Microtubule Binding Kinesin Binding Kinase Binding GABA Receptor Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Regulatory Region DNA Binding Intronic Transcription Regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Enzyme Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Intronic Transcription Regulatory Region DNA Binding
	Biological Process	Protein Transport Cognition	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Phospholipid Metabolic Process Axon Guidance Brain Development Endoderm Development Locomotory Behavior Response To Hormone Positive Regulation Of Gene Expression Negative Regulation Of Epithelial To Mesenchymal Transition Globus Pallidus Development Hippocampus Development Cerebral Cortex Cell Migration Forebrain Dorsal/ventral Pattern Formation Forebrain Neuron Fate Commitment Cerebral Cortex GABAergic Interneuron Differentiation Pituitary Gland Development Cell Differentiation Lung Development Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Thyroid Gland Development Forebrain Development Developmental Induction Leydig Cell Differentiation Positive Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Rhythmic Process Anatomical Structure Formation Involved In Morphogenesis Oligodendrocyte Differentiation Lung Saccule Development Epithelial Tube Branching Involved In Lung Morphogenesis Clara Cell Differentiation Type II Pneumocyte Differentiation
Pathways
Drugs
Diseases			Choreoathetosis, hypothyroidism, and neonatal respiratory distress
GWAS		Coronary artery disease in type 1 diabetes ( 29695241) Response to angiotensin II receptor blocker therapy ( 22566498) Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901)	Differentiated thyroid cancer ( 28703219) Height ( 18391950) Menarche (age at onset) ( 23667675 29773799) Papillary thyroid cancer ( 28703219) Thyroid cancer ( 19198613)
Interacting Genes		12 interacting genes: BOD1L1 CLNK GABBR1 HTRA3 JAK1 MKX MRFAP1L1 NKX2-1 TADA2B TRMT44 TYK2 YWHAG	15 interacting genes: CALR CAVIN1 CREBBP GATA6 HIPK2 JAKMIP1 MAPK1 NCOA1 NCOA2 NCOA3 PAX8 RARA RELA TDG WWTR1
Entrez ID		152789	7080
HPRD ID		11292	02798
Ensembl ID		ENSG00000152969	ENSG00000136352
Uniprot IDs		B3KWB6 Q96N16	P43699
PDB IDs
Enriched GO Terms of Interacting Partners?
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