CTBP2 and RPL7A

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		CTBP2	RPL7A
Description		C-terminal binding protein 2	ribosomal protein L7a
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GO Annotations	Cellular Component	Nucleus Transcriptional Repressor Complex Cell Junction Photoreceptor Ribbon Synapse Presynaptic Active Zone Cytoplasmic Component Glutamatergic Synapse GABA-ergic Synapse Presynaptic Cytosol	Nucleus Nucleolus Cytoplasm Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Polysomal Ribosome Synapse
	Molecular Function	Chromatin Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Protein Kinase Binding Retinoic Acid Receptor Binding Protein-containing Complex Binding NAD Binding Structural Constituent Of Presynaptic Active Zone	RNA Binding Structural Constituent Of Ribosome Protein Binding Cadherin Binding
	Biological Process	Negative Regulation Of Cell Proliferation Synaptic Vesicle Docking Viral Genome Replication Positive Regulation Of Chromatin Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Maintenance Of Presynaptic Active Zone Structure White Fat Cell Differentiation Oxidation-reduction Process Cellular Response To Leukemia Inhibitory Factor	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maturation Of LSU-rRNA Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription
Pathways		Repression of WNT target genes TCF7L2 mutants don't bind CTBP	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Age-related cognitive decline (visuospatial skill) (slope of z-scores) ( 30954325) Body mass index ( 25673413 29273807) Chronotype ( 30696823) Diastolic blood pressure ( 30224653) Height ( 25429064) Infant, child and juvenile death in continuous marriage (proportion of children died <15 years) ( 30188897) Menarche (age at onset) ( 25231870) Prostate cancer ( 18264096) Vigorous physical activity ( 29899525)	Blood protein levels ( 28240269)
Interacting Genes		67 interacting genes: ACTG1 AKTIP APP ATE1 BAZ2B BCAS3 BCL3 C15orf39 CASP8AP2 CBX4 CCNH CCR5 CDKN2A CTBP1 CTPS2 DMRTB1 DVL2 EEF1D ELAC2 EP300 FHL3 FLI1 FOXP2 FUNDC1 H3-4 HIC1 HOXB5 IKZF2 KCNIP3 KLF3 KLF8 MDM2 MECOM NOL4 NOL4L NRIP1 PLCB1 PNN PPP1R15A PROX1 PSMF1 RAI2 RIMBP3 RPL17 RPL7A RPS28 RPS29 RPS4X RUNX1 SOX13 SOX6 STUB1 STX11 TEAD3 TGIF1 TSHZ3 UBC UBE2I XRCC6 ZBP1 ZBTB18 ZEB1 ZEB2 ZFPM1 ZFPM2 ZNF512B ZNF750	7 interacting genes: CCDC47 CTBP2 MKNK2 POLR2M SGO1 SOCS3 STAU1
Entrez ID		1488	6130
HPRD ID		04016	01712
Ensembl ID		ENSG00000175029	ENSG00000148303
Uniprot IDs		P56545	P62424
PDB IDs		2OME 4LCJ	4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
Enriched GO Terms of Interacting Partners?
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