KASH5 and BET1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KASH5	BET1
Description		KASH domain containing 5	Bet1 golgi vesicular membrane trafficking protein
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Lateral Element Cell Nuclear Outer Membrane Integral Component Of Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex Meiotic Spindle Pole	Golgi Trans Cisterna Golgi Membrane Endoplasmic Reticulum Membrane Membrane Transport Vesicle Integral Component Of Golgi Membrane SNARE Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Protein Binding Identical Protein Binding Dynein Complex Binding	SNAP Receptor Activity Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Actin Filament Organization Synapsis Spermatogenesis Telomere Localization Oogenesis Spindle Assembly Spindle Localization Microtubule Cytoskeleton Organization Involved In Homologous Chromosome Segregation Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation	ER To Golgi Vesicle-mediated Transport Protein Transport COPII Vesicle Coating Vesicle Fusion With Golgi Apparatus
Pathways			COPII-mediated vesicle transport COPI-mediated anterograde transport
Drugs
Diseases
GWAS			Aging ( 22773346) Asparaginase hypersensitivity in acute lymphoblastic leukemia ( 25987655) BRCA1/2-negative high-risk breast cancer ( 30323354) Obesity-related traits ( 23251661) World class endurance athleticism ( 26824906)
Interacting Genes		76 interacting genes: ABHD1 ADIPOQ ATF7 BAG5 BCL2L2 BET1 CCDC87 CDC73 CDKL3 CIB3 CLDN8 CRABP2 CXCL16 CXCL9 CYBC1 EMD FAM161A FAM90A1 FATE1 FIS1 FRA10AC1 FTCD GABARAPL2 GALNT2 GOSR2 GPATCH4 GPR25 HMOX1 ITM2B JAGN1 KDM1A LARP1 LAT LENG1 LHFPL5 LMNA MALL MARCHF2 MFSD5 MMP14 MS4A1 MTX2 NRIP3 NSG1 NTAQ1 OLFM4 PDGFRA PLP2 PPP1R18 RIPPLY2 RNF146 RSRC2 RTP2 SENP2 SERP2 SGTA SHMT2 SLC30A2 SLC41A2 SLN SMCO4 STBD1 STX5 TCF25 TMEM11 TMEM14C TMEM199 TMEM41A TMPRSS4 TRAF3IP3 TSHZ3 UPK1B UPK2 VAMP1 VAMP4 ZNF250	9 interacting genes: BCL2L13 FAM9B KASH5 MAGEA6 PLEKHA5 SNTG2 STX4 STX5 USHBP1
Entrez ID		147872	10282
HPRD ID		08134	16107
Ensembl ID		ENSG00000161609	ENSG00000105829
Uniprot IDs		Q8N6L0	O15155 Q53XK0
PDB IDs			3EGX
Enriched GO Terms of Interacting Partners?
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