CCBE1 and STX11

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CCBE1	STX11
Description		collagen and calcium binding EGF domains 1	syntaxin 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Collagen Trimer Extracellular Space Extracellular Matrix	Golgi Apparatus Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane SNARE Complex Presynaptic Membrane Presynaptic Active Zone Membrane
	Molecular Function	Protease Binding Calcium Ion Binding Protein Binding Collagen Binding	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Lymphangiogenesis Sprouting Angiogenesis Respiratory System Process Positive Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Protein Processing Lung Development Positive Regulation Of Angiogenesis Venous Blood Vessel Morphogenesis Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Lymphangiogenesis	Intracellular Protein Transport Exocytosis Vesicle Fusion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Membrane Fusion
Pathways
Drugs
Diseases			Familial hemophagocytic lymphohistiocytosis (FHPL), including the following three diseases: Perforin deficiency; Munc deficiency; STX11 deficiency
GWAS		Age-related hearing impairment ( 24939585) Major depressive disorder ( 23857890) Pre-treatment viral load in HIV-1 infection ( 31219150)	Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		6 interacting genes: CEP55 FBXO7 KLHL12 SIAH2 STX11 TOX4	64 interacting genes: APP AXIN1 BLOC1S6 BYSL C1orf109 CARD9 CCBE1 CCDC184 CCDC33 CCNK CDCA7L CRYBA4 CTBP2 CWF19L2 EIF1AD FAM110A FAM161A FAM74A4 FAM90A1 FARS2 GOLGA8EP GOLGA8F HAUS1 HGS IKBKG IKZF3 KAT5 KCTD9 KDM1A KLC3 KXD1 LENG1 LONRF1 MBIP MEOX2 MFAP1 MID2 NDC80 NTAQ1 PPP1R18 PRKAB2 PRPF31 PSMA3 PSMC3 RNF6 RUNX1T1 SH2D4A SLC38A2 SMARCE1 SNAP23 SNAP25 SNX3 SUV39H1 TAF6L TBK1 TCF4 TLE5 TNFRSF21 USHBP1 VAMP2 VPS52 ZCCHC10 ZNF417 ZNF587
Entrez ID		147372	8676
HPRD ID		08703	09231
Ensembl ID		ENSG00000183287	ENSG00000135604
Uniprot IDs		Q6UXH8	O75558
PDB IDs
Enriched GO Terms of Interacting Partners?
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