CRIP2 and GATA6

Number of citations of the paper that reports this interaction (PubMedID 12530967)
83

Data Source:
HPRD (in vivo, in vitro)

		CRIP2	GATA6
Description		cysteine rich protein 2	GATA binding protein 6
Image			No pdb structure
GO Annotations	Cellular Component	Cell Cortex	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Nuclear Membrane
	Molecular Function	Protein Binding Zinc Ion Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Repressing Transcription Factor Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Protein Kinase Binding Transcription Regulatory Region DNA Binding
	Biological Process	Positive Regulation Of Cell Proliferation Hemopoiesis	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Liver Development Outflow Tract Septum Morphogenesis Type B Pancreatic Cell Differentiation Pancreatic A Cell Differentiation Transcription By RNA Polymerase II Phospholipid Metabolic Process Endodermal Cell Fate Determination Blood Coagulation Male Gonad Development Cardiac Muscle Hypertrophy In Response To Stress Epithelial Cell Differentiation Negative Regulation Of Transforming Growth Factor Beta1 Production Negative Regulation Of Transforming Growth Factor Beta2 Production Tube Morphogenesis Response To Drug Negative Regulation Of Apoptotic Process Response To Estrogen Cellular Protein Metabolic Process Cell Fate Commitment Positive Regulation Of Angiogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Animal Organ Formation Smooth Muscle Cell Differentiation Positive Regulation Of Cardioblast Differentiation Cardiac Muscle Cell Differentiation Positive Regulation Of Cardiac Muscle Cell Proliferation Lung Saccule Development Clara Cell Differentiation Type II Pneumocyte Differentiation Intestinal Epithelial Cell Differentiation Cardiac Vascular Smooth Muscle Cell Differentiation Response To Growth Factor Positive Regulation Of Cell Cycle Arrest Cellular Response To Gonadotropin Stimulus Cellular Response To Hypoxia Cellular Response To BMP Stimulus Positive Regulation Of Cardiac Muscle Myoblast Proliferation
Pathways			Surfactant metabolism Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Diverticular disease ( 30177863) Endometrial cancer ( 30093612) Endometrial cancer (endometrioid histology) ( 30093612) LDL cholesterol ( 25961943) Lung function (FEV1/FVC) ( 30804560) Resting heart rate ( 27798624) Severe progression in rheumatoid arthritis ( 29065906) Tuberculosis ( 20694014)
Interacting Genes		17 interacting genes: APP ATN1 ATP1B1 ATXN1 GADD45G GATA4 GATA6 KLF10 NOTCH3 OSGEP PCYT2 PRKG1 PTPN13 SMN1 SPRY2 SRF TK1	7 interacting genes: CRIP2 EP300 HHEX KLF2 KPNA3 MED1 NKX2-1
Entrez ID		1397	2627
HPRD ID		03113	09043
Ensembl ID		ENSG00000182809	ENSG00000141448
Uniprot IDs		P52943	Q92908
PDB IDs		2CU8
Enriched GO Terms of Interacting Partners?
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